nature.com ꯗꯥ ꯆꯪꯕꯤꯕꯒꯤꯗꯃꯛ ꯊꯥꯒꯠꯆꯔꯤ꯫ ꯅꯍꯥꯛꯅꯥ ꯁꯤꯖꯤꯟꯅꯔꯤꯕꯥ ꯕ꯭ꯔꯥꯎꯖꯔ ꯚꯔꯁꯟ ꯑꯗꯨꯗꯥ ꯂꯤꯃꯤꯇꯦꯗ CSS ꯁꯄꯣꯔꯠ ꯂꯩ꯫ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯐꯕꯥ ꯑꯦꯛꯁꯄꯤꯔꯤꯑꯦꯟꯁꯀꯤꯗꯃꯛꯇꯥ, ꯅꯍꯥꯛꯅꯥ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯅꯧꯕꯥ ꯕ꯭ꯔꯥꯎꯖꯔ ꯚꯔꯁꯟ (ꯅꯠꯠꯔꯒꯥ ꯏꯟꯇꯔꯅꯦꯠ ꯑꯦꯛꯁꯞꯂꯣꯌꯥꯔꯗꯥ ꯀꯝꯄꯦꯇꯤꯕꯤꯂꯤꯇꯤ ꯃꯣꯗ ꯑꯣꯐ ꯇꯧꯕꯥ) ꯁꯤꯖꯤꯟꯅꯅꯕꯥ ꯑꯩꯈꯣꯌꯅꯥ ꯇꯀꯁꯤꯜꯂꯤ꯫ ꯃꯁꯤꯒꯤ ꯃꯊꯛꯇꯥ, ꯃꯈꯥ ꯇꯥꯅꯥ ꯁꯄꯣꯔꯠ ꯇꯧꯕꯥ ꯉꯝꯅꯕꯥ, ꯁꯥꯏꯠ ꯑꯁꯤꯅꯥ ꯁ꯭ꯇꯥꯏꯜ ꯅꯠꯔꯒꯥ ꯖꯥꯚꯥꯁ꯭ꯛꯔꯤꯞꯇ ꯌꯥꯑꯣꯔꯣꯏ꯫
ꯁꯤꯟꯊꯣꯟ ꯳-(ꯑꯦꯟꯊ꯭ꯔꯥꯁꯦꯟ-꯹-ꯏꯜ)-꯲-ꯁꯥꯏꯅꯣꯑꯦꯛꯔꯤꯂꯣꯏꯜ ꯀ꯭ꯂꯣꯔꯥꯏꯗ ꯴ ꯑꯁꯤ ꯁꯤꯟꯊꯦꯁꯤꯁ ꯇꯧꯈꯤ ꯑꯃꯁꯨꯡ ꯇꯣꯉꯥꯟ ꯇꯣꯉꯥꯅꯕꯥ ꯅꯥꯏꯠꯔꯣꯖꯦꯟ ꯅ꯭ꯌꯨꯛꯂꯤꯑꯣꯐꯥꯏꯂꯁꯤꯡꯒꯥ ꯃꯁꯤꯒꯤ ꯔꯤꯑꯦꯛꯁꯅꯒꯤ ꯈꯨꯠꯊꯥꯡꯗꯥ ꯃꯈꯜ ꯀꯌꯥꯒꯤ ꯌꯥꯝꯅꯥ ꯑꯦꯛꯇꯤꯕ ꯑꯣꯏꯕꯥ ꯍꯦꯇꯦꯔꯣꯁꯥꯏꯛꯂꯤꯛ ꯀꯝꯄꯥꯎꯟꯗꯁꯤꯡ ꯁꯤꯟꯊꯦꯁꯤꯁ ꯇꯧꯕꯗꯥ ꯁꯤꯖꯤꯟꯅꯈꯤ꯫ ꯁꯤꯟꯊꯦꯁꯤꯁ ꯇꯧꯔꯕꯥ ꯍꯦꯇꯦꯔꯣꯁꯥꯏꯛꯂꯤꯛ ꯀꯝꯄꯥꯎꯟꯗ ꯈꯨꯗꯤꯡꯃꯛꯀꯤ ꯁ꯭ꯠꯔꯀꯆꯔ ꯑꯁꯤ ꯁ꯭ꯄꯦꯛꯠꯔꯣꯁ꯭ꯀꯣꯄꯤꯛ ꯑꯃꯁꯨꯡ ꯏꯂꯤꯃꯦꯟꯇꯔꯤ ꯑꯦꯅꯥꯂꯥꯏꯁꯤꯁ ꯁꯤꯖꯤꯟꯅꯗꯨꯅꯥ ꯃꯄꯨꯡ ꯐꯥꯅꯥ ꯃꯁꯛ ꯇꯥꯀꯈꯤ꯫ ꯅꯣꯚꯦꯜ ꯍꯦꯇꯦꯔꯣꯁꯥꯏꯛꯂꯤꯛ ꯀꯝꯄꯥꯎꯟꯗ ꯇꯔꯥꯒꯤ ꯃꯅꯨꯡꯗꯥ ꯱꯰ꯅꯥ ꯃꯜꯇꯤꯗ꯭ꯔꯒ-ꯔꯦꯁꯤꯁ꯭ꯇꯦꯟꯇ ꯕꯦꯛꯇꯦꯔꯤꯌꯥ (ꯑꯦꯝ.ꯑꯥꯔ.ꯑꯦꯁ.ꯑꯦ.)ꯒꯤ ꯃꯥꯌꯣꯛꯇꯥ ꯄꯨꯛꯅꯤꯡ ꯊꯧꯒꯠꯅꯤꯡꯉꯥꯏ ꯑꯣꯏꯕꯥ ꯏꯐꯤꯁꯤꯑꯦꯟꯁꯤ ꯎꯠꯈꯤ꯫ ꯃꯈꯣꯌꯒꯤ ꯃꯅꯨꯡꯗꯥ ꯀꯝꯄꯥꯎꯟꯗ ꯶, ꯷, ꯱꯰, ꯱꯳ꯕꯤ, ꯑꯃꯁꯨꯡ ꯱꯴ꯅꯥ ꯁꯦꯟꯇꯤꯃꯤꯇꯔ ꯴ꯒꯥ ꯅꯛꯅꯕꯥ ꯏꯅꯍꯤꯕꯤꯁꯟ ꯖꯣꯅꯁꯤꯡꯒꯥ ꯂꯣꯌꯅꯅꯥ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯋꯥꯡꯕꯥ ꯑꯦꯟꯇꯤꯕꯦꯛꯇꯦꯔꯤꯑꯦꯜ ꯑꯦꯛꯇꯤꯚꯤꯇꯤ ꯎꯠꯈꯤ꯫ ꯑꯗꯨꯝ ꯑꯣꯏꯅꯃꯛ, ꯃꯣꯂꯤꯛꯌꯨꯂꯔ ꯗꯣꯀꯤꯡ ꯁ꯭ꯇꯗꯤꯁꯤꯡꯅꯥ ꯀꯝꯄꯣꯅꯦꯟꯇꯁꯤꯡ ꯑꯁꯤꯅꯥ ꯑꯦꯝ.ꯑꯥꯔ.ꯑꯦꯁ.ꯑꯦ.ꯒꯤ ꯔꯦꯁꯤꯁ꯭ꯇꯦꯟꯁꯀꯤ ꯃꯔꯨꯑꯣꯏꯕꯥ ꯄꯥꯟꯗꯝ ꯑꯃꯥ ꯑꯣꯏꯔꯤꯕꯥ ꯄꯦꯅꯤꯁꯤꯂꯤꯟ-ꯕꯥꯏꯟꯗꯤꯡ ꯄ꯭ꯔꯣꯇꯤꯟ ꯲ꯑꯦ (ꯄꯤ.ꯕꯤ.ꯄꯤ.꯲ꯑꯦ. ꯷, ꯱꯰ ꯑꯃꯁꯨꯡ ꯱꯴ꯒꯨꯝꯕꯥ ꯀꯝꯄꯣꯅꯦꯟꯇ ꯈꯔꯅꯥ ꯀꯣ-ꯀ꯭ꯔꯤꯁ꯭ꯇꯦꯂꯥꯏꯖ ꯇꯧꯔꯕꯥ ꯀꯨꯏꯅꯥꯖꯣꯂꯤꯅꯣꯟ ꯂꯤꯒꯦꯟꯗꯒꯥ ꯆꯥꯡꯗꯝꯅꯕꯗꯥ ꯄꯤ.ꯕꯤ.ꯄꯤ.꯲ꯑꯦ.ꯒꯤ ꯑꯦꯛꯇꯤꯕ ꯁꯥꯏꯠꯇꯥ ꯍꯦꯟꯅꯥ ꯋꯥꯡꯕꯥ ꯕꯥꯏꯟꯗꯤꯡ ꯑꯦꯐꯤꯅꯤꯇꯤ ꯑꯃꯁꯨꯡ ꯏꯟꯇꯔꯦꯛꯁꯟ ꯁ꯭ꯇꯦꯕꯤꯂꯤꯇꯤ ꯎꯠꯈꯤ꯫ ꯃꯁꯤꯒꯥ ꯃꯥꯟꯅꯅꯥ, ꯀꯝꯄꯥꯎꯟꯗ ꯶ ꯑꯃꯁꯨꯡ ꯱꯳ꯕꯤꯅꯥ ꯗꯣꯀꯤꯡ ꯁ꯭ꯀꯣꯔꯁꯤꯡ ꯍꯦꯟꯅꯥ ꯅꯦꯝꯅꯥ ꯂꯩꯈꯤ ꯑꯗꯨꯕꯨ ꯍꯧꯖꯤꯀꯁꯨ ꯃꯔꯨ ꯑꯣꯏꯕꯥ ꯑꯦꯟꯇꯤꯕꯦꯛꯇꯦꯔꯤꯑꯦꯜ ꯑꯦꯛꯇꯤꯚꯤꯇꯤ ꯎꯠꯈꯤ, ꯃꯁꯤꯗꯥ ꯀꯝꯄꯣꯁ꯭ꯠ ꯶ꯅꯥ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯅꯦꯝꯕꯥ ꯑꯦꯝ.ꯑꯥꯏ.ꯁꯤ.(꯹.꯷ μg/꯱꯰꯰ μL) ꯑꯃꯁꯨꯡ ꯑꯦꯝ.ꯕꯤ.ꯁꯤ.(꯷꯸.꯱꯲꯵ μg/꯱꯰꯰ μL) ꯚꯦꯜꯌꯨꯁꯤꯡ ꯂꯩꯈꯤ꯫ ꯗꯣꯀꯤꯡ ꯑꯦꯅꯥꯂꯥꯏꯁꯤꯁꯅꯥ ꯍꯥꯏꯗ꯭ꯔꯣꯖꯦꯟ ꯕꯣꯟꯗꯤꯡ ꯑꯃꯁꯨꯡ π-ꯁ꯭ꯇꯦꯀꯤꯡ ꯌꯥꯑꯣꯅꯥ ꯃꯔꯨꯑꯣꯏꯕꯥ ꯏꯟꯇꯔꯦꯛꯁꯅꯁꯤꯡ ꯎꯕꯥ ꯐꯪꯈꯤ, ꯃꯔꯨꯑꯣꯏꯅꯥ Lys 273, Lys 316 ꯑꯃꯁꯨꯡ Arg 298ꯒꯨꯝꯕꯥ ꯔꯦꯁꯤꯗꯦꯟꯇꯁꯤꯡꯒꯥ ꯂꯣꯌꯅꯅꯥ, ꯃꯈꯣꯌꯁꯤꯡ ꯑꯁꯤ PBP2aꯒꯤ ꯀ꯭ꯔꯤꯁ꯭ꯇꯦꯜ ꯁ꯭ꯠꯔꯀꯆꯔꯗꯥ ꯀꯣ-ꯀ꯭ꯔꯤꯁ꯭ꯇꯦꯂꯥꯏꯖ ꯇꯧꯔꯕꯥ ꯂꯤꯒꯦꯟꯗꯒꯥ ꯏꯟꯇꯔꯦꯛꯇ ꯇꯧꯕꯥ ꯍꯥꯌꯅꯥ ꯈꯉꯗꯣꯀꯈꯤ꯫ ꯍꯥꯌꯔꯤꯕꯥ ꯔꯦꯁꯤꯗꯦꯟꯇꯁꯤꯡ ꯑꯁꯤ ꯄꯤ.ꯕꯤ.ꯄꯤ.꯲ꯑꯦ.ꯒꯤ ꯑꯦꯅꯖꯥꯏꯃꯦꯇꯤꯛ ꯑꯦꯛꯇꯤꯚꯤꯇꯤꯒꯤꯗꯃꯛꯇꯥ ꯌꯥꯝꯅꯥ ꯃꯔꯨꯑꯣꯏ꯫ ꯃꯁꯤꯒꯤ ꯔꯤꯖꯜꯇꯁꯤꯡ ꯑꯁꯤꯅꯥ ꯇꯥꯛꯂꯤ ꯃꯗꯨꯗꯤ ꯁꯤꯟꯊꯦꯁꯤꯁ ꯇꯧꯔꯕꯥ ꯀꯝꯄꯥꯎꯟꯗꯁꯤꯡ ꯑꯁꯤꯅꯥ ꯊꯥꯖꯅꯤꯡꯉꯥꯏ ꯑꯣꯏꯕꯥ ꯑꯦꯟꯇꯤ-ꯑꯦꯝ.ꯑꯥꯔ.ꯑꯦꯁ.ꯑꯦ.
ꯆꯍꯤꯆꯥ ꯑꯁꯤꯒꯤ ꯑꯍꯥꯅꯕꯥ ꯆꯍꯤ ꯈꯔꯗꯥ ꯔꯤꯁꯔꯆꯀꯤ ꯍꯣꯠꯅꯔꯤꯕꯁꯤꯡ ꯑꯁꯤ ꯃꯔꯨꯑꯣꯏꯅꯥ ꯌꯥꯝꯅꯥ ꯂꯥꯏꯅꯥ ꯐꯪꯒꯗꯕꯥ ꯍꯧꯔꯀꯐꯝ ꯃꯆꯥꯀꯁꯤꯡ ꯁꯤꯖꯤꯟꯅꯗꯨꯅꯥ ꯑꯦꯟꯇꯤꯃꯥꯏꯛꯔꯣꯕꯤꯌꯥꯜ ꯑꯦꯛꯇꯤꯚꯤꯇꯤ ꯂꯩꯕꯥ ꯑꯅꯧꯕꯥ ꯍꯦꯇꯦꯔꯣꯁꯥꯏꯛꯂꯤꯛ ꯁꯤꯁ꯭ꯇꯦꯝ ꯀꯌꯥ ꯑꯃꯥ ꯁꯦꯃꯒꯠꯅꯕꯥ ꯑꯅꯧꯕꯥ, ꯏꯆꯝ ꯆꯝꯕꯥ ꯊꯧꯑꯣꯡꯁꯤꯡ ꯑꯃꯁꯨꯡ ꯄꯥꯝꯕꯩꯁꯤꯡ ꯁꯦꯃꯒꯠꯄꯗꯥ ꯃꯤꯠꯌꯦꯡ ꯊꯃꯈꯤ꯫
ꯑꯦꯛꯔꯤꯂꯣꯅꯥꯏꯠꯔꯥꯏꯜ ꯃꯣꯏꯇꯤꯁꯤꯡ ꯑꯁꯤ ꯁꯤꯡꯊꯥꯅꯤꯡꯉꯥꯏ ꯑꯣꯏꯕꯥ ꯍꯦꯇꯦꯔꯣꯁꯥꯏꯛꯂꯤꯛ ꯁꯤꯁ꯭ꯇꯦꯝ ꯀꯌꯥꯒꯤ ꯁꯤꯟꯊꯦꯁꯤꯁꯀꯤꯗꯃꯛꯇꯥ ꯃꯔꯨꯑꯣꯏꯕꯥ ꯍꯧꯔꯀꯐꯝ ꯑꯣꯏꯅꯥ ꯂꯧꯅꯩ ꯃꯔꯃꯗꯤ ꯃꯈꯣꯌ ꯑꯁꯤ ꯌꯥꯝꯅꯥ ꯔꯤꯑꯦꯛꯇꯤꯕ ꯑꯣꯏꯕꯥ ꯀꯝꯄꯥꯎꯟꯗꯁꯤꯡꯅꯤ꯫ ꯃꯁꯤꯒꯤ ꯃꯊꯛꯇꯥ, ꯲-ꯁꯥꯏꯅꯣꯑꯦꯛꯔꯤꯂꯣꯏꯜ ꯀ꯭ꯂꯣꯔꯥꯏꯗ ꯗꯦꯔꯤꯕꯦꯇꯤꯕꯁꯤꯡ ꯑꯁꯤ ꯍꯧꯈꯤꯕꯥ ꯆꯍꯤ ꯈꯔꯁꯤꯗꯥ ꯐꯥꯔꯃꯥꯀꯣꯂꯣꯖꯤꯀꯦꯜ ꯑꯦꯞꯂꯤꯀꯦꯁꯅꯁꯤꯡꯒꯤ ꯂꯃꯗꯥ ꯌꯥꯝꯅꯥ ꯃꯔꯨꯑꯣꯏꯕꯥ ꯄꯣꯠꯊꯣꯀꯁꯤꯡ ꯁꯦꯃꯒꯠꯄꯥ ꯑꯃꯁꯨꯡ ꯁꯤꯟꯊꯦꯁꯤꯁ ꯇꯧꯕꯗꯥ ꯄꯥꯛ ꯁꯟꯅꯥ ​​ꯁꯤꯖꯤꯟꯅꯈ꯭ꯔꯦ, ꯃꯈꯣꯌꯁꯤꯡ ꯑꯗꯨꯗꯤ ꯗ꯭ꯔꯒ ꯏꯟꯇꯔꯃꯦꯗꯤꯑꯦꯠꯁꯤꯡ꯱,꯲,꯳, ꯑꯦꯟꯇꯤ-ꯑꯩꯆ.ꯑꯥꯏ.ꯚꯤ. ꯍꯟꯗꯛꯀꯤ ꯃꯇꯝ ꯑꯁꯤꯗꯥ ꯑꯦꯟꯊ꯭ꯔꯥꯁꯤꯟ ꯑꯃꯁꯨꯡ ꯃꯁꯤꯒꯤ ꯗꯦꯔꯤꯕꯦꯇꯤꯕꯁꯤꯡꯒꯤ ꯕꯥꯏꯑꯣꯂꯣꯖꯤꯀꯦꯜ ꯏꯐꯤꯁꯤꯑꯦꯟꯁꯤ, ꯃꯈꯣꯌꯒꯤ ꯑꯦꯟꯇꯤꯕꯥꯏꯑꯣꯇꯤꯛ, ꯑꯦꯟꯇꯤꯀꯦꯟꯁꯔ꯱꯱,꯱꯲, ꯑꯦꯟꯇꯤꯕꯦꯛꯇꯦꯔꯤꯑꯦꯜ꯱꯳,꯱꯴,꯱꯵ ꯑꯃꯁꯨꯡ ꯏꯅꯁꯦꯛꯇꯤꯁꯥꯏꯗꯜ ꯄ꯭ꯔꯣꯄꯔꯇꯤꯁꯤꯡ꯱꯶,꯱꯷ ꯑꯁꯤꯅꯥ ꯌꯥꯝꯅꯥ ꯄꯨꯛꯅꯤꯡ ꯆꯤꯡꯁꯤꯜꯂꯦ18,19,20,21꯫ ꯑꯦꯛꯔꯤꯂꯣꯅꯥꯏꯠꯔꯥꯏꯜ ꯑꯃꯁꯨꯡ ꯑꯦꯟꯊ꯭ꯔꯥꯁꯤꯟ ꯃꯣꯏꯇꯤꯁꯤꯡ ꯌꯥꯑꯣꯕꯥ ꯑꯦꯟꯇꯤꯃꯥꯏꯛꯔꯣꯕꯤꯌꯥꯜ ꯀꯝꯄꯥꯎꯟꯗꯁꯤꯡ ꯑꯁꯤ ꯐꯤꯒꯔ ꯱ ꯑꯃꯁꯨꯡ ꯲ꯗꯥ ꯎꯠꯂꯤ꯫
ꯋꯥꯔꯜꯗ ꯍꯦꯜꯊ ꯑꯣꯔꯒꯅꯥꯏꯖꯦꯁꯟ (ꯗꯕꯜꯌꯨ.ꯑꯩꯆ.ꯑꯣ.) (꯲꯰꯲꯱)ꯒꯤ ꯃꯇꯨꯡ ꯏꯟꯅꯥ ꯑꯦꯟꯇꯤꯃꯥꯏꯛꯔꯣꯕꯤꯌꯥꯜ ꯔꯦꯁꯤꯁ꯭ꯇꯦꯟꯁ (ꯑꯦ.ꯑꯦꯝ.ꯑꯥꯔ.) ꯑꯁꯤ ꯍꯀꯁꯦꯜ ꯑꯃꯁꯨꯡ ꯆꯥꯎꯈꯠꯄꯗꯥ ꯃꯥꯂꯦꯃꯒꯤ ꯑꯣꯏꯅꯥ ꯈꯨꯗꯣꯡꯊꯤꯕꯥ ꯑꯃꯥ ꯑꯣꯏꯔꯤ22,23,24,25꯫ ꯄꯦꯁꯦꯟꯇꯁꯤꯡ ꯐꯍꯅꯕꯥ ꯉꯃꯗꯦ, ꯃꯁꯤꯅꯥ ꯃꯔꯝ ꯑꯣꯏꯗꯨꯅꯥ ꯍꯣꯁ꯭ꯄꯤꯇꯥꯂꯗꯥ ꯃꯇꯝ ꯁꯥꯡꯅꯥ ꯂꯩꯕꯥ ꯑꯃꯁꯨꯡ ꯃꯃꯜ ꯌꯥꯝꯂꯕꯥ ꯗ꯭ꯔꯒꯁꯤꯡꯒꯤ ꯃꯊꯧ ꯇꯥꯕꯥ ꯍꯦꯅꯒꯠꯂꯀꯄꯒꯥ ꯂꯣꯌꯅꯅꯥ ꯁꯤꯕꯒꯤ ꯆꯥꯡ ꯑꯃꯁꯨꯡ ꯗꯤꯁꯑꯦꯕꯤꯂꯤꯇꯤ ꯍꯦꯅꯒꯠꯂꯀꯏ꯫ ꯏꯐꯦꯛꯇꯤꯚ ꯑꯣꯏꯕꯥ ꯑꯦꯟꯇꯤꯃꯥꯏꯛꯔꯣꯕꯤꯌꯥꯂꯁꯤꯡ ꯂꯩꯇꯕꯅꯥ ꯑꯌꯥꯝꯕꯗꯤ ꯃꯔꯨꯑꯣꯏꯅꯥ ꯀꯦꯃꯣꯊꯦꯔꯥꯄꯤ ꯑꯃꯁꯨꯡ ꯑꯆꯧꯕꯥ ꯁꯔꯖꯔꯤꯒꯤ ꯃꯇꯃꯗꯥ ꯇꯣꯉꯥꯟ-ꯇꯣꯉꯥꯅꯕꯥ ꯏꯅꯐꯦꯛꯁꯅꯁꯤꯡꯒꯤ ꯂꯥꯏꯌꯦꯡ ꯐꯜ ꯊꯣꯀꯍꯜꯂꯤ꯫
ꯋꯥꯔꯜꯗ ꯍꯦꯜꯊ ꯑꯣꯔꯒꯅꯥꯏꯖꯦꯁꯟ ꯲꯰꯲꯴ꯒꯤ ꯔꯤꯄꯣꯔꯇꯀꯤ ꯃꯇꯨꯡ ꯏꯟꯅꯥ ꯃꯦꯊꯤꯁꯤꯂꯤꯟ ꯔꯦꯁꯤꯁ꯭ꯇꯦꯟꯇ ꯁ꯭ꯇꯦꯐꯥꯏꯂꯣꯀꯣꯀꯁ ꯑꯣꯔꯦꯁ (ꯑꯦꯝ.ꯑꯥꯔ.ꯑꯦꯁ.ꯑꯦ.) ꯑꯃꯁꯨꯡ ꯏ. ꯕꯦꯛꯇꯦꯔꯤꯌꯥ ꯑꯅꯤꯃꯛ ꯑꯁꯤ ꯑꯦꯟꯇꯤꯕꯥꯏꯑꯣꯇꯤꯛ ꯀꯌꯥꯗꯥ ꯔꯦꯁꯤꯁ꯭ꯇꯦꯟꯇ ꯑꯣꯏ, ꯃꯔꯝ ꯑꯗꯨꯅꯥ ꯃꯈꯣꯌꯅꯥ ꯂꯥꯌꯦꯡꯕꯗꯥ ꯑꯃꯁꯨꯡ ꯀꯟꯠꯔꯣꯜ ꯇꯧꯕꯗꯥ ꯑꯋꯥꯕꯥ ꯏꯅꯐꯦꯛꯁꯅꯁꯤꯡ ꯔꯤꯞꯔꯖꯦꯟꯇ ꯇꯧꯔꯤ, ꯑꯃꯁꯨꯡ ꯃꯁꯤꯒꯤ ꯁꯃꯁ꯭ꯌꯥ ꯑꯁꯤ ꯀꯣꯀꯍꯟꯅꯕꯥ ꯑꯅꯧꯕꯥ ꯑꯃꯁꯨꯡ ꯏꯐꯦꯛꯇꯤꯕ ꯑꯣꯏꯕꯥ ꯑꯦꯟꯇꯤꯃꯥꯏꯛꯔꯣꯕꯤꯌꯥꯜ ꯀꯝꯄꯥꯎꯟꯗꯁꯤꯡ ꯄꯨꯊꯣꯀꯄꯒꯤ ꯈꯨꯗꯛꯀꯤ ꯑꯣꯏꯕꯥ ꯃꯊꯧ ꯇꯥꯕꯥ ꯂꯩ꯫ ꯑꯦꯟꯊ꯭ꯔꯥꯁꯤꯟ ꯑꯃꯁꯨꯡ ꯃꯁꯤꯒꯤ ꯗꯦꯔꯤꯕꯦꯇꯤꯕꯁꯤꯡ ꯑꯁꯤ ꯒ꯭ꯔꯥꯝ-ꯄꯣꯖꯤꯇꯤꯕ ꯑꯃꯁꯨꯡ ꯒ꯭ꯔꯥꯝ-ꯅꯦꯒꯦꯇꯤꯕ ꯕꯦꯛꯇꯦꯔꯤꯌꯥ ꯑꯅꯤꯃꯛꯇꯥ ꯊꯕꯛ ꯇꯧꯕꯥ ꯉꯝꯕꯥ ꯃꯃꯤꯡ ꯂꯩꯔꯕꯥ ꯑꯦꯟꯇꯤꯃꯥꯏꯛꯔꯣꯕꯤꯌꯥꯂꯁꯤꯡꯅꯤ꯫ ꯁ꯭ꯇꯗꯤ ꯑꯁꯤꯒꯤ ꯄꯥꯟꯗꯃꯗꯤ ꯍꯀꯁꯦꯂꯗꯥ ꯈꯨꯗꯣꯡꯊꯤꯅꯤꯡꯉꯥꯏ ꯑꯣꯏꯕꯥ ꯄꯦꯊꯣꯖꯦꯅꯁꯤꯡ ꯑꯁꯤ ꯊꯦꯡꯅꯕꯥ ꯉꯝꯕꯥ ꯑꯅꯧꯕꯥ ꯗꯦꯔꯤꯕꯦꯇꯤꯕ ꯑꯃꯥ ꯁꯤꯟꯊꯦꯁꯤꯁ ꯇꯧꯕꯅꯤ꯫
ꯋꯥꯔꯜꯗ ꯍꯦꯜꯊ ꯑꯣꯔꯒꯅꯥꯏꯖꯦꯁꯟ (ꯗꯕꯜꯌꯨ.ꯑꯩꯆ.ꯑꯣ.)ꯅꯥ ꯔꯤꯄꯣꯔꯠ ꯇꯧꯔꯀꯄꯒꯤ ꯃꯇꯨꯡ ꯏꯟꯅꯥ ꯕꯦꯛꯇꯦꯔꯤꯌꯥꯒꯤ ꯄꯦꯊꯣꯖꯦꯟ ꯀꯌꯥꯅꯥ ꯃꯁꯤꯡ ꯌꯥꯝꯂꯕꯥ ꯑꯦꯟꯇꯤꯕꯥꯏꯑꯣꯇꯤꯀꯁꯤꯡꯗꯥ ꯔꯦꯁꯤꯁ꯭ꯇꯦꯟꯇ ꯑꯣꯏꯔꯤ, ꯃꯗꯨꯒꯤ ꯃꯅꯨꯡꯗꯥ ꯀꯝꯌꯨꯅꯤꯇꯤ ꯑꯃꯁꯨꯡ ꯍꯦꯜꯊ ꯀꯦꯌꯔ ꯁꯦꯇꯤꯡꯁꯤꯡꯗꯥ ꯏꯅꯐꯦꯛꯁꯅꯒꯤ ꯀꯃꯟ ꯑꯣꯏꯕꯥ ꯃꯔꯝ ꯑꯃꯥ ꯑꯣꯏꯔꯤꯕꯥ ꯃꯦꯊꯤꯁꯤꯂꯤꯟ ꯔꯦꯁꯤꯁ꯭ꯇꯦꯟꯇ ꯁ꯭ꯇꯦꯐꯥꯏꯂꯣꯀꯣꯀꯁ ꯑꯣꯔꯦꯁ (ꯑꯦꯝ.ꯑꯥꯔ.ꯑꯦꯁ.ꯑꯦ.) ꯌꯥꯑꯣꯔꯤ꯫ ꯑꯦꯝ.ꯑꯥꯔ.ꯑꯦꯁ.ꯑꯦ.ꯒꯤ ꯏꯅꯐꯦꯛꯁꯟ ꯂꯩꯕꯥ ꯄꯦꯁꯦꯟꯇꯁꯤꯡꯅꯥ ꯗ꯭ꯔꯒ-ꯁꯁ꯭ꯄꯦꯛꯇꯤꯕ ꯏꯅꯐꯦꯛꯁꯟ ꯂꯩꯕꯥ ꯄꯦꯁꯦꯟꯇꯁꯤꯡꯗꯒꯤ ꯁꯤꯕꯒꯤ ꯆꯥꯡ ꯑꯁꯤ ꯶꯴% ꯍꯦꯟꯅꯥ ꯋꯥꯡꯏ ꯍꯥꯌꯅꯥ ꯄꯥꯎꯗꯝꯂꯤ꯫ ꯃꯁꯤꯒꯤ ꯃꯊꯛꯇꯥ, ꯏ.ꯀꯣꯂꯤꯅꯥ ꯃꯥꯂꯦꯃꯒꯤ ꯑꯣꯏꯅꯥ ꯈꯨꯗꯣꯡꯊꯤꯕꯥ ꯑꯃꯥ ꯊꯣꯀꯍꯜꯂꯤ ꯃꯔꯃꯗꯤ ꯀꯥꯔꯕꯥꯄꯦꯅꯦꯝ-ꯔꯦꯁꯤꯁ꯭ꯇꯦꯟꯇ ꯑꯦꯟꯇꯦꯔꯣꯕꯦꯛꯇꯦꯔꯤꯑꯦꯁꯤꯌꯥ (ꯑꯔꯕꯥꯟ, ꯏ. ꯀꯣꯂꯤ)ꯒꯤ ꯃꯥꯌꯣꯛꯇꯥ ꯑꯔꯣꯏꯕꯥ ꯗꯤꯐꯦꯟꯁ ꯂꯥꯏꯟ ꯑꯁꯤ ꯀꯣꯂꯤꯁ꯭ꯇꯤꯅꯅꯤ, ꯑꯗꯨꯕꯨ ꯀꯣꯂꯤꯁ꯭ꯇꯤꯟ-ꯔꯦꯁꯤꯁ꯭ꯇꯦꯟꯇ ꯕꯦꯛꯇꯦꯔꯤꯌꯥ ꯑꯁꯤ ꯍꯟꯗꯛꯇꯥ ꯂꯩꯕꯥꯛ ꯀꯌꯥꯗꯥ ꯔꯤꯄꯣꯔꯠ ꯇꯧꯈ꯭ꯔꯦ꯫ ꯲꯲,꯲꯳,꯲꯴,꯲꯵ ꯑꯣꯏꯈꯤ꯫
ꯃꯔꯝ ꯑꯗꯨꯅꯥ ꯋꯥꯔꯜꯗ ꯍꯦꯜꯊ ꯑꯣꯔꯒꯅꯥꯏꯖꯦꯁꯅꯒꯤ ꯒ꯭ꯂꯣꯕꯦꯜ ꯑꯦꯛꯁꯟ ꯄ꯭ꯂꯥꯟ ꯑꯣꯟ ꯑꯦꯟꯇꯤꯃꯥꯏꯛꯔꯣꯕꯤꯌꯥꯜ ꯔꯦꯁꯤꯁ꯭ꯇꯦꯟꯁ26ꯒꯤ ꯃꯇꯨꯡ ꯏꯟꯅꯥ ꯑꯅꯧꯕꯥ ꯑꯦꯟꯇꯤꯃꯥꯏꯛꯔꯣꯕꯤꯌꯥꯂꯁꯤꯡ ꯊꯤꯗꯣꯀꯄꯥ ꯑꯃꯁꯨꯡ ꯁꯤꯟꯊꯦꯁꯤꯁ ꯇꯧꯕꯒꯤ ꯈꯨꯗꯛꯀꯤ ꯑꯣꯏꯕꯥ ꯃꯊꯧ ꯇꯥꯕꯥ ꯑꯃꯥ ꯂꯩꯔꯤ꯫ ꯑꯦꯟꯇꯤꯕꯦꯛꯇꯦꯔꯤꯑꯦꯜ꯲꯷, ꯑꯦꯟꯇꯤꯐꯉ꯭ꯒꯦꯂ꯲꯸, ꯑꯦꯟꯇꯤꯀꯦꯟꯁꯔ꯲꯹ ꯑꯃꯁꯨꯡ ꯑꯦꯟꯇꯤꯑꯣꯛꯁꯤꯗꯦꯟꯇ꯳꯰ ꯑꯦꯖꯦꯟꯇ ꯑꯣꯏꯅꯥ ꯑꯦꯟꯊ꯭ꯔꯥꯁꯤꯟ ꯑꯃꯁꯨꯡ ꯑꯦꯛꯔꯤꯂꯣꯅꯥꯏꯠꯔꯥꯏꯂꯒꯤ ꯑꯆꯧꯕꯥ ꯄꯣꯇꯦꯟꯁꯤꯌꯦꯜ ꯑꯁꯤ ꯐꯣꯉꯕꯥ ꯄꯦꯄꯔ ꯀꯌꯥꯗꯥ ꯐꯣꯉꯗꯣꯀꯈ꯭ꯔꯦ꯫ ꯃꯁꯤꯒꯤ ꯃꯇꯥꯡꯗꯥ ꯍꯥꯌꯕꯥ ꯌꯥꯏ ꯃꯗꯨꯗꯤ ꯍꯥꯌꯔꯤꯕꯥ ꯗꯦꯔꯤꯕꯦꯇꯤꯕꯁꯤꯡ ꯑꯁꯤ ꯃꯦꯊꯤꯁꯤꯂꯤꯟ-ꯔꯦꯁꯤꯁ꯭ꯇꯦꯟꯇ ꯁ꯭ꯇꯥꯐꯥꯏꯂꯣꯀꯣꯀꯁ ꯑꯣꯔꯦꯁ (ꯑꯦꯝ.ꯑꯥꯔ.ꯑꯦꯁ.ꯑꯦ.)ꯒꯤ ꯃꯥꯌꯣꯛꯇꯥ ꯁꯤꯖꯤꯟꯅꯕꯒꯤ ꯑꯐꯕꯥ ꯀꯦꯟꯗꯤꯗꯦꯠꯁꯤꯡꯅꯤ꯫
ꯃꯃꯥꯡꯒꯤ ꯂꯤꯇꯔꯦꯆꯔ ꯔꯤꯚꯤꯌꯨꯁꯤꯡꯅꯥ ꯑꯩꯈꯣꯌꯕꯨ ꯀ꯭ꯂꯥꯁꯁꯤꯡ ꯑꯁꯤꯗꯥ ꯑꯅꯧꯕꯥ ꯗꯦꯔꯤꯕꯦꯇꯤꯕꯁꯤꯡ ꯁꯤꯟꯊꯦꯁꯤꯁ ꯇꯧꯅꯕꯥ ꯄꯨꯛꯅꯤꯡ ꯊꯧꯒꯠꯈꯤ꯫ ꯃꯔꯝ ꯑꯁꯤꯅꯥ ꯍꯧꯖꯤꯛ ꯄꯥꯡꯊꯣꯛꯂꯤꯕꯥ ꯊꯤꯖꯤꯅꯕꯒꯤ ꯊꯕꯛ ꯑꯁꯤꯅꯥ ꯑꯦꯟꯊ꯭ꯔꯥꯁꯤꯟ ꯑꯃꯁꯨꯡ ꯑꯦꯛꯔꯤꯂꯣꯅꯥꯏꯠꯔꯥꯏꯜ ꯃꯣꯏꯇꯤꯁꯤꯡ ꯌꯥꯑꯣꯕꯥ ꯑꯅꯧꯕꯥ ꯍꯦꯇꯦꯔꯣꯁꯥꯏꯛꯂꯤꯛ ꯁꯤꯁ꯭ꯇꯦꯃꯁꯤꯡ ꯁꯦꯃꯒꯠꯅꯕꯥ, ꯃꯈꯣꯌꯒꯤ ꯑꯦꯟꯇꯤꯃꯥꯏꯛꯔꯣꯕꯤꯌꯥꯜ ꯑꯃꯁꯨꯡ ꯑꯦꯟꯇꯤꯕꯦꯛꯇꯦꯔꯤꯑꯦꯜ ꯏꯐꯤꯁꯤꯑꯦꯟꯁꯤ ꯏꯚꯥꯂꯨꯑꯦꯠ ꯇꯧꯅꯕꯥ ꯑꯃꯁꯨꯡ ꯃꯣꯂꯤꯛꯌꯨꯂꯔ ꯗꯣꯛ ꯇꯧꯗꯨꯅꯥ ꯄꯦꯅꯤꯁꯤꯂꯤꯟ-ꯕꯥꯏꯟꯗꯤꯡ ꯄ꯭ꯔꯣꯇꯤꯟ ꯲ꯑꯦ (ꯄꯤ.ꯕꯤ.ꯄꯤ.꯲ꯑꯦ.)ꯒꯥ ꯃꯈꯣꯌꯒꯤ ꯑꯣꯏꯊꯣꯀꯄꯥ ꯌꯥꯕꯥ ꯕꯥꯏꯟꯗꯤꯡ ꯏꯟꯇꯔꯦꯛꯁꯅꯁꯤꯡ ꯊꯤꯖꯤꯟꯅꯕꯥ ꯄꯥꯟꯗꯝ ꯊꯝꯂꯤ꯫ ꯃꯃꯥꯡꯒꯤ ꯁ꯭ꯇꯗꯤꯁꯤꯡꯗꯥ ꯌꯨꯝꯐꯝ ꯑꯣꯏꯗꯨꯅꯥ ꯍꯧꯖꯤꯛ ꯄꯥꯡꯊꯣꯛꯂꯤꯕꯥ ꯊꯤꯖꯤꯅꯕꯒꯤ ꯊꯕꯛ ꯑꯁꯤꯅꯥ ꯍꯦꯇꯦꯔꯣꯁꯥꯏꯛꯂꯤꯛ ꯁꯤꯁ꯭ꯇꯦꯃꯁꯤꯡꯒꯤ ꯁꯤꯟꯊꯦꯁꯤꯁ, ꯕꯥꯏꯑꯣꯂꯣꯖꯤꯀꯦꯜ ꯏꯚꯥꯂꯨꯑꯦꯁꯟ, ꯑꯃꯁꯨꯡ ꯀꯝꯞꯌꯨꯇꯦꯁ꯭ꯅꯦꯜ ꯑꯦꯅꯥꯂꯥꯏꯁꯤꯁ ꯃꯈꯥ ꯆꯠꯊꯗꯨꯅꯥ ꯃꯄꯥꯉ꯭ꯒꯜ ꯀꯅꯕꯥ ꯄꯤ.ꯕꯤ.ꯄꯤ.꯲ꯑꯦ ꯑꯦꯛꯇꯤꯕꯤꯇꯤ꯳꯱,꯳꯲,꯳꯳,꯳꯴,꯳꯵,꯳꯶,꯳꯷,꯳꯸,꯳꯹,꯴꯰,꯴꯱,꯴꯲,꯴꯳,꯴꯴,꯴꯵,꯴꯶,꯴꯷,꯴꯸,꯴꯹.
ꯑꯩꯈꯣꯌꯒꯤ ꯍꯧꯖꯤꯛ ꯄꯥꯡꯊꯣꯛꯂꯤꯕꯥ ꯔꯤꯁꯔꯆ ꯑꯁꯤꯅꯥ ꯑꯦꯟꯊ꯭ꯔꯥꯁꯤꯟ ꯑꯃꯁꯨꯡ ꯑꯦꯛꯔꯤꯂꯣꯅꯥꯏꯠꯔꯥꯏꯜ ꯃꯣꯏꯇꯤꯁꯤꯡ ꯌꯥꯑꯣꯕꯥ ꯅꯣꯕꯦꯜ ꯍꯦꯇꯦꯔꯣꯁꯥꯏꯛꯂꯤꯛ ꯀꯝꯄꯥꯎꯟꯗꯁꯤꯡꯒꯤ ꯁꯤꯟꯊꯦꯁꯤꯁ ꯑꯃꯁꯨꯡ ꯑꯦꯟꯇꯤꯃꯥꯏꯛꯔꯣꯕꯤꯌꯥꯜ ꯏꯚꯥꯂꯨꯑꯦꯁꯅꯗꯥ ꯃꯤꯠꯌꯦꯡ ꯊꯝꯂꯤ꯫ ꯳-(ꯑꯦꯟꯊ꯭ꯔꯥꯁꯦꯟ-꯹-ꯏꯜ)-꯲-ꯁꯥꯏꯅꯣꯑꯦꯛꯔꯤꯂꯣꯏꯜ ꯀ꯭ꯂꯣꯔꯥꯏꯗ ꯴ ꯁꯦꯃꯈꯤ ꯑꯃꯁꯨꯡ ꯑꯅꯧꯕꯥ ꯍꯦꯇꯦꯔꯣꯁꯥꯏꯛꯂꯤꯛ ꯁꯤꯁ꯭ꯇꯦꯃꯁꯤꯡ ꯁꯦꯃꯒꯠꯅꯕꯥ ꯕꯤꯜꯗꯤꯡ ꯕ꯭ꯂꯣꯛ ꯑꯃꯥ ꯑꯣꯏꯅꯥ ꯁꯤꯖꯤꯟꯅꯈꯤ꯫
ꯀꯝꯄꯥꯎꯟꯗ ꯴ꯒꯤ ꯁ꯭ꯠꯔꯀꯆꯔ ꯑꯁꯤ ꯁ꯭ꯄꯦꯛꯠꯔꯜ ꯗꯦꯇꯥ ꯁꯤꯖꯤꯟꯅꯗꯨꯅꯥ ꯂꯦꯄꯈꯤ꯫ 1H-NMR ꯁ꯭ꯄꯦꯛꯠꯔꯦꯃꯅꯥ ꯄꯤ.ꯄꯤ.ꯑꯦꯝ.ꯗꯥ ꯹.꯲꯶ꯗꯥ ꯁꯤ.ꯑꯩꯆ.= ꯂꯩꯕꯥ ꯎꯠꯈꯤ, ꯑꯥꯏ.ꯑꯥꯔ.
꯳-(ꯑꯦꯟꯊ꯭ꯔꯥꯁꯦꯟ-꯹-ꯏꯜ)-꯲-ꯁꯥꯏꯅꯣꯑꯦꯛꯔꯤꯂꯣꯏꯜ ꯀ꯭ꯂꯣꯔꯥꯏꯗ ꯴ꯒꯤ ꯁꯤꯟꯊꯦꯁꯤꯁ ꯑꯁꯤ ꯏꯊꯥꯅꯣꯂꯤꯛ ꯁꯣꯗꯤꯌꯝ ꯍꯥꯏꯗ꯭ꯔꯣꯛꯁꯥꯏꯗ ꯁꯣꯜꯌꯨꯁꯟ (꯱꯰%)ꯒꯥ ꯂꯣꯌꯅꯅꯥ ꯑꯦꯔꯣꯃꯦꯇꯤꯛ ꯒ꯭ꯔꯨꯞ ꯲꯵꯰, ꯴꯱, ꯴꯲, ꯵꯳ ꯍꯥꯏꯗ꯭ꯔꯣꯂꯥꯏꯁꯤꯁ ꯇꯧꯗꯨꯅꯥ ꯑꯦꯁꯤꯗ ꯳꯵꯴, ꯴꯵, ꯵꯶ ꯄꯤꯗꯨꯅꯥ ꯄꯥꯡꯊꯣꯀꯈꯤ, ꯃꯗꯨꯒꯤ ꯃꯇꯨꯡꯗꯥ ꯏꯁꯤꯡꯒꯤ ꯕꯥꯊꯇꯥ ꯊꯥꯏꯑꯣꯅꯥꯏꯜ ꯀ꯭ꯂꯣꯔꯥꯏꯗꯅꯥ ꯇ꯭ꯔꯤꯠ ꯇꯧꯗꯨꯅꯥ ꯄꯤꯈꯤ꯫ ꯐꯤꯒꯔ ꯳ꯗꯥ ꯎꯠꯂꯤꯕꯥ ꯃꯇꯨꯡ ꯏꯟꯅꯥ ꯑꯋꯥꯡꯕꯥ ꯄꯣꯠꯊꯣꯛ (꯸꯸.꯵%)ꯗꯥ ꯑꯦꯛꯔꯤꯂꯣꯏꯜ ꯀ꯭ꯂꯣꯔꯥꯏꯗ ꯗꯦꯔꯤꯕꯦꯇꯤꯕ ꯴ ꯌꯥꯑꯣꯔꯤ꯫
ꯊꯥꯖꯕꯥ ꯌꯥꯕꯥ ꯑꯦꯟꯇꯤꯕꯦꯛꯇꯦꯔꯤꯑꯦꯜ ꯏꯐꯤꯁꯤꯑꯦꯟꯁꯤ ꯂꯩꯕꯥ ꯑꯅꯧꯕꯥ ꯍꯦꯇꯦꯔꯣꯁꯥꯏꯛꯂꯤꯛ ꯀꯝꯄꯥꯎꯟꯗꯁꯤꯡ ꯁꯦꯃꯒꯠꯅꯕꯥ, ꯇꯣꯉꯥꯟ ꯇꯣꯉꯥꯅꯕꯥ ꯗꯥꯏꯅꯨꯛꯂꯤꯑꯣꯐꯥꯏꯂꯁꯤꯡꯒꯥ ꯂꯣꯌꯅꯅꯥ ꯑꯦꯁꯤꯜ ꯀ꯭ꯂꯣꯔꯥꯏꯗ ꯴ꯒꯤ ꯔꯤꯑꯦꯛꯁꯟ ꯄꯥꯡꯊꯣꯀꯈꯤ꯫
ꯑꯦꯁꯤꯗ ꯀ꯭ꯂꯣꯔꯥꯏꯗ 4 ꯑꯗꯨ ꯍꯥꯏꯗ꯭ꯔꯣꯖꯦꯟ ꯍꯥꯏꯗ꯭ꯔꯦꯠꯅꯥ 0°ꯗꯥ ꯄꯨꯡ ꯑꯃꯥ ꯊꯤꯡꯖꯤꯅꯈꯤ꯫ ꯅꯨꯡꯉꯥꯏꯇꯕꯥ ꯋꯥꯐꯝ ꯑꯃꯅꯥ ꯄꯥꯏꯔꯥꯖꯣꯂꯣꯟ ꯵ ꯐꯪꯈꯤꯗꯦ꯫ ꯄꯣꯠꯊꯣꯛ ꯑꯁꯤ ꯑꯦꯛꯔꯦꯂꯥꯃꯥꯏꯗ ꯗꯦꯔꯤꯕꯦꯇꯤꯕ ꯑꯃꯅꯤ ꯃꯁꯤꯒꯤ ꯁ꯭ꯠꯔꯀꯆꯔ ꯑꯁꯤ ꯁ꯭ꯄꯦꯛꯠꯔꯜ ꯗꯦꯇꯥꯅꯥ ꯀꯅꯐꯔꯝ ꯇꯧꯈꯤ꯫ ꯃꯁꯤꯒꯤ ꯑꯥꯏ.ꯑꯥꯔ. ꯱ꯑꯩꯆ-ꯑꯦꯟ.ꯑꯦꯝ.ꯑꯥꯔ.ꯒꯤ ꯁ꯭ꯄꯦꯛꯠꯔꯦꯝ ꯑꯁꯤꯅꯥ ꯑꯣꯂꯦꯐꯤꯟ ꯄ꯭ꯔꯣꯇꯣꯅꯁꯤꯡ ꯑꯃꯁꯨꯡ ꯑꯦꯟ.ꯑꯩꯆ.ꯄ꯭ꯔꯣꯇꯣꯅꯁꯤꯡꯒꯤ ꯑꯦꯛꯁꯆꯦꯟꯖ ꯁꯤꯉ꯭ꯒꯜ ꯁꯤꯒꯅꯦꯜ ꯑꯃꯥ ꯹.꯳ ꯄꯤ.ꯄꯤ.ꯑꯦꯝ.ꯗꯥ ꯎꯠꯈꯤ (ꯑꯦꯛꯁꯄꯤꯔꯤꯃꯦꯟꯇ ꯁꯦꯛꯁꯟ ꯌꯦꯡꯕꯤꯌꯨ)꯫
ꯑꯦꯁꯤꯗ ꯀ꯭ꯂꯣꯔꯥꯏꯗ ꯴ꯒꯤ ꯃꯣꯜ ꯑꯅꯤ ꯑꯁꯤ ꯐꯦꯅꯤꯂꯍꯥꯏꯗ꯭ꯔꯥꯖꯤꯅꯒꯤ ꯃꯣꯜ ꯑꯃꯒꯥ ꯔꯤꯑꯦꯛꯇ ꯇꯧꯗꯨꯅꯥ ꯑꯐꯕꯥ ꯄꯣꯠꯊꯣꯛ (꯷꯷%)ꯗꯥ N-ꯐꯦꯅꯤꯂꯛꯔꯥꯏꯂꯣꯏꯂꯍꯥꯏꯗ꯭ꯔꯥꯖꯤꯟ ꯗꯦꯔꯤꯕꯦꯇꯤꯕ ꯷ ꯄꯤꯈꯤ (ꯆꯤꯠꯔ ꯵)꯫ ꯷ꯀꯤ ꯁ꯭ꯠꯔꯀꯆꯔ ꯑꯁꯤ ꯏꯅꯐ꯭ꯔꯥꯔꯦꯗ ꯁ꯭ꯄꯦꯛꯠꯔꯣꯁ꯭ꯀꯣꯄꯤ ꯗꯦꯇꯥꯅꯥ ꯀꯅꯐꯔꯝ ꯇꯧꯈꯤ, ꯃꯁꯤꯅꯥ ꯱꯶꯹꯱ ꯑꯃꯁꯨꯡ ꯱꯶꯷꯱ ꯁꯦ.ꯃꯤ.−꯱ꯗꯥ ꯁꯤ=ꯑꯣ ꯀꯥꯡꯂꯨꯞ ꯑꯅꯤ ꯑꯦꯕꯁꯣꯔꯞ ꯇꯧꯕꯥ, ꯁꯤ.ꯑꯦꯟ.ꯒꯤ ꯀꯥꯡꯂꯨꯞ ꯲꯲꯲꯲ ꯁꯦ.ꯃꯤ.−꯱ꯗꯥ ꯑꯃꯁꯨꯡ ꯑꯦꯟ.ꯑꯩꯆ ꯄ꯭ꯔꯣꯇꯣꯟ ꯑꯁꯤ 10.88 ppmꯗꯥ (ꯑꯦꯛꯁꯄꯤꯔꯤꯃꯦꯟꯇ ꯁꯦꯛꯁꯟ ꯌꯦꯡꯎ)꯫
ꯁ꯭ꯇꯗꯤ ꯑꯁꯤꯗꯥ ꯑꯦꯁꯤꯜ ꯀ꯭ꯂꯣꯔꯥꯏꯗ ꯴ꯒꯤ ꯔꯤꯑꯦꯛꯁꯟ ꯑꯁꯤ ꯱,꯳-ꯗꯥꯏꯅꯨꯛꯂꯤꯑꯣꯐꯥꯏꯂꯁꯤꯡꯒꯥ ꯂꯣꯌꯅꯅꯥ ꯊꯤꯖꯤꯅꯈꯤ꯫ ꯔꯨꯝ ꯇꯦꯝꯄꯦꯔꯦꯆꯔꯗꯥ ꯕꯦꯖ ꯑꯣꯏꯅꯥ ꯇꯤ.ꯏ.ꯑꯦ.ꯒꯥ ꯂꯣꯌꯅꯅꯥ ꯱,꯴-ꯗꯥꯏꯑꯣꯛꯁꯦꯅꯗꯥ ꯲-ꯑꯦꯃꯤꯅꯣꯄꯥꯏꯔꯤꯗꯤꯅꯒꯥ ꯂꯣꯌꯅꯅꯥ ꯑꯦꯁꯤꯜ ꯀ꯭ꯂꯣꯔꯥꯏꯗ ꯴ ꯂꯥꯌꯦꯡꯕꯅꯥ ꯑꯦꯛꯔꯤꯂꯥꯃꯥꯏꯗ ꯗꯦꯔꯤꯕꯦꯇꯤꯕ ꯸ (ꯆꯤꯠꯔ ꯵) ꯐꯪꯈꯤ, ꯃꯁꯤꯒꯤ ꯁ꯭ꯠꯔꯀꯆꯔ ꯑꯁꯤ ꯁ꯭ꯄꯦꯛꯠꯔꯜ ꯗꯦꯇꯥ ꯁꯤꯖꯤꯟꯅꯗꯨꯅꯥ ꯈꯉꯗꯣꯀꯈꯤ꯫ ꯑꯥꯏ.ꯑꯥꯔ.ꯒꯤ ꯁ꯭ꯄꯦꯛꯠꯔꯥꯅꯥ ꯁꯥꯏꯅꯣꯒꯤ ꯑꯦꯕꯁꯣꯔꯄꯁꯟ ꯕꯦꯟꯗꯁꯤꯡ ꯲꯲꯲꯲ ꯁꯦ.ꯃꯤ.−꯱ꯗꯥ, ꯑꯦꯟ.ꯑꯩꯆ.ꯅꯥ ꯳꯱꯴꯸ ꯁꯦ.ꯃꯤ.−꯱ꯗꯥ, ꯑꯃꯁꯨꯡ ꯀꯥꯔꯕꯣꯅꯥꯏꯂꯒꯤ ꯑꯦꯕꯁꯣꯔꯄꯁꯟ ꯕꯦꯟꯗꯁꯤꯡ ꯱꯶꯶꯵ ꯁꯦ.ꯃꯤ.−꯱ꯗꯥ ꯎꯠꯈꯤ; ꯱ꯑꯩꯆ ꯑꯦꯟ.ꯑꯦꯝ.ꯑꯥꯔ.ꯒꯤ ꯁ꯭ꯄꯦꯛꯠꯔꯥꯅꯥ ꯹.꯱꯴ ꯄꯤ.ꯄꯤ.ꯑꯦꯝ.ꯗꯥ ꯑꯣꯂꯦꯐꯤꯟ ꯄ꯭ꯔꯣꯇꯣꯅꯁꯤꯡ ꯂꯩꯕꯥ ꯀꯅꯐꯔꯝ ꯇꯧꯈꯤ (ꯑꯦꯛꯁꯄꯤꯔꯤꯃꯦꯟꯇ ꯁꯦꯛꯁꯟ ꯌꯦꯡꯕꯤꯌꯨ)꯫
ꯀꯝꯄꯣꯁ꯭ꯠ 4ꯅꯥ ꯊꯥꯏꯑꯣꯌꯨꯔꯤꯌꯥꯒꯥ ꯔꯤꯑꯦꯛꯇ ꯇꯧꯗꯨꯅꯥ ꯄꯥꯏꯔꯤꯃꯤꯗꯤꯅꯦꯊꯤꯑꯣꯟ 9 ꯄꯤ; ꯀꯝꯄꯣꯁ꯭ꯠ 4ꯅꯥ ꯊꯥꯏꯑꯣꯁꯦꯃꯤꯀꯥꯔꯕꯥꯖꯤꯗꯀꯥ ꯔꯤꯑꯦꯛꯇ ꯇꯧꯗꯨꯅꯥ ꯊꯥꯏꯑꯣꯄꯥꯏꯔꯥꯖꯣꯜ ꯗꯦꯔꯤꯕꯦꯇꯤꯚ 10 ꯄꯤ (ꯐꯤꯒꯔ 5)꯫ ꯀꯝꯄꯥꯎꯟꯗ ꯹ ꯑꯃꯁꯨꯡ ꯱꯰ꯒꯤ ꯁ꯭ꯠꯔꯀꯆꯔꯁꯤꯡ ꯑꯁꯤ ꯁ꯭ꯄꯦꯛꯠꯔꯜ ꯑꯃꯁꯨꯡ ꯏꯂꯤꯃꯦꯟꯇꯔꯤ ꯑꯦꯅꯥꯂꯥꯏꯁꯤꯁꯅꯥ ꯀꯅꯐꯔꯝ ꯇꯧꯈꯤ (ꯑꯦꯛꯁꯄꯤꯔꯤꯃꯦꯟꯇ ꯁꯦꯛꯁꯟ ꯌꯦꯡꯕꯤꯌꯨ)꯫
ꯇꯦꯠꯔꯥꯖꯤꯟ-꯳-ꯊꯥꯏꯑꯣꯜ ꯱꯱ ꯑꯁꯤ ꯀꯝꯄꯣꯁ꯭ꯠ ꯴ ꯑꯁꯤ ꯊꯥꯏꯑꯣꯀꯥꯔꯕꯥꯖꯥꯏꯗꯀꯥ ꯱,꯴-ꯗꯥꯏꯅꯨꯛꯂꯤꯑꯣꯐꯥꯏꯜ ꯑꯣꯏꯅꯥ ꯔꯤꯑꯦꯛꯁꯟ ꯇꯧꯗꯨꯅꯥ ꯁꯦꯃꯈꯤ (ꯆꯤꯠꯔ ꯵), ꯑꯃꯁꯨꯡ ꯃꯁꯤꯒꯤ ꯁ꯭ꯠꯔꯀꯆꯔ ꯑꯁꯤ ꯁ꯭ꯄꯦꯛꯠꯔꯣꯁ꯭ꯀꯣꯄꯤ ꯑꯃꯁꯨꯡ ꯏꯂꯤꯃꯦꯟꯇꯔꯤ ꯑꯦꯅꯥꯂꯥꯏꯁꯤꯁꯅꯥ ꯀꯅꯐꯔꯝ ꯇꯧꯈꯤ꯫ ꯏꯅꯐ꯭ꯔꯥꯔꯦꯗ ꯁ꯭ꯄꯦꯛꯠꯔꯦꯃꯗꯥ, C=N ꯕꯣꯟꯗ ꯑꯁꯤ 1619 cm−1ꯗꯥ ꯎꯕꯥ ꯐꯪꯈꯤ꯫ ꯃꯇꯝ ꯑꯗꯨꯃꯛꯇꯗꯥ, ꯃꯁꯤꯒꯤ ꯱ꯑꯩꯆ-ꯑꯦꯟ.ꯑꯦꯝ.ꯑꯥꯔ.ꯒꯤ ꯁ꯭ꯄꯦꯛꯠꯔꯦꯃꯅꯥ ꯷.꯷꯸–꯸.꯶꯶ ꯄꯤ.ꯄꯤ.ꯑꯦꯝ.ꯗꯥ ꯑꯦꯔꯣꯃꯦꯇꯤꯛ ꯄ꯭ꯔꯣꯇꯣꯅꯁꯤꯡꯒꯤ ꯃꯜꯇꯤꯞꯂꯦꯠ ꯁꯤꯒꯅꯦꯂꯁꯤꯡ ꯑꯃꯁꯨꯡ ꯳.꯳꯱ ꯄꯤ.ꯄꯤ.ꯑꯦꯝ.ꯗꯥ ꯑꯦꯁ.ꯑꯩꯆ.
ꯑꯦꯛꯔꯤꯂꯣꯏꯜ ꯀ꯭ꯂꯣꯔꯥꯏꯗ ꯴ꯅꯥ ꯱,꯲-ꯗꯥꯏꯑꯦꯃꯤꯅꯣꯕꯦꯟꯖꯤꯟ, ꯲-ꯑꯦꯃꯤꯅꯣꯊꯥꯏꯑꯣꯐꯦꯅꯣꯜ, ꯑꯦꯟꯊ꯭ꯔꯥꯅꯤꯂꯤꯛ ꯑꯦꯁꯤꯗ, ꯱,꯲-ꯗꯥꯏꯑꯦꯃꯤꯅꯣꯏꯊꯦꯟ, ꯑꯃꯁꯨꯡ ꯏꯊꯥꯅꯣꯂꯥꯃꯥꯏꯅꯒꯥ ꯂꯣꯌꯅꯅꯥ ꯱,꯴-ꯗꯥꯏꯅꯨꯛꯂꯤꯑꯣꯐꯥꯏꯜ ꯑꯣꯏꯅꯥ ꯔꯤꯑꯦꯛꯇ ꯇꯧꯗꯨꯅꯥ ꯑꯅꯧꯕꯥ ꯍꯦꯇꯦꯔꯣꯁꯥꯏꯛꯂꯤꯛ ꯁꯤꯁ꯭ꯇꯦꯃꯁꯤꯡ ꯁꯦꯝꯃꯤ (꯱꯳–꯱꯶)꯫
ꯅꯧꯅꯥ ꯁꯦꯃꯈꯤꯕꯥ ꯀꯝꯄꯥꯎꯟꯗꯁꯤꯡ ꯑꯁꯤꯒꯤ ꯁ꯭ꯠꯔꯀꯆꯔꯁꯤꯡ ꯑꯁꯤ ꯁ꯭ꯄꯦꯛꯠꯔꯜ ꯑꯃꯁꯨꯡ ꯏꯂꯤꯃꯦꯟꯇꯔꯤ ꯑꯦꯅꯥꯂꯥꯏꯁꯤꯁꯅꯥ ꯀꯅꯐꯔꯝ ꯇꯧꯈꯤ (ꯑꯦꯛꯁꯄꯤꯔꯤꯃꯦꯟꯇ ꯁꯦꯛꯁꯟ ꯌꯦꯡꯕꯤꯌꯨ)꯫ ꯲-ꯍꯥꯏꯗ꯭ꯔꯣꯛꯁꯤꯐꯦꯅꯤꯂꯥꯛꯔꯤꯂꯥꯃꯥꯏꯗ ꯗꯦꯔꯤꯕꯦꯇꯤꯕ ꯱꯷ ꯑꯁꯤ ꯲-ꯑꯦꯃꯤꯅꯣꯐꯦꯅꯣꯂꯒꯥ ꯂꯣꯌꯅꯅꯥ ꯗꯥꯏꯅꯨꯛꯂꯤꯑꯣꯐꯥꯏꯜ ꯑꯣꯏꯅꯥ ꯔꯤꯑꯦꯛꯁꯟ ꯇꯧꯗꯨꯅꯥ ꯐꯪꯈꯤ (ꯆꯤꯠꯔ ꯶), ꯑꯃꯁꯨꯡ ꯃꯁꯤꯒꯤ ꯁ꯭ꯠꯔꯀꯆꯔ ꯑꯁꯤ ꯁ꯭ꯄꯦꯛꯠꯔꯜ ꯑꯃꯁꯨꯡ ꯏꯂꯤꯃꯦꯟꯇꯔꯤ ꯑꯦꯅꯥꯂꯥꯏꯁꯤꯁꯅꯥ ꯀꯅꯐꯔꯝ ꯇꯧꯈꯤ꯫ ꯀꯝꯄꯥꯎꯟꯗ ꯱꯷ꯀꯤ ꯏꯅꯐ꯭ꯔꯥꯔꯦꯗ ꯁ꯭ꯄꯦꯛꯠꯔꯦꯃꯅꯥ ꯁꯤ=ꯑꯣ ꯑꯃꯁꯨꯡ ꯁꯤ≡N ꯁꯤꯒꯅꯦꯂꯁꯤꯡ ꯑꯁꯤ ꯃꯊꯪꯁꯤꯠꯅꯥ ꯱꯶꯸꯱ ꯑꯃꯁꯨꯡ ꯲꯲꯲꯶ ꯁꯦ.ꯃꯤ.−꯱ꯗꯥ ꯎꯕꯥ ꯐꯪꯈꯤ꯫ ꯃꯁꯤꯒꯤ ꯃꯅꯨꯡꯗꯥ, ꯃꯁꯤꯒꯤ ꯱ꯑꯩꯆ-ꯑꯦꯟ.ꯑꯦꯝ.ꯑꯥꯔ.ꯒꯤ ꯁ꯭ꯄꯦꯛꯠꯔꯦꯃꯅꯥ ꯑꯣꯂꯦꯐꯤꯟ ꯄ꯭ꯔꯣꯇꯣꯅꯒꯤ ꯁꯤꯉ꯭ꯒꯜ ꯁꯤꯒꯅꯦꯜ ꯑꯁꯤ ꯹.꯱꯹ ꯄꯤ.ꯄꯤ.ꯑꯦꯝ.ꯗꯥ ꯊꯃꯈꯤ, ꯑꯃꯁꯨꯡ ꯑꯣ.ꯑꯩꯆ.
ꯑꯦꯁꯤꯗ ꯀ꯭ꯂꯣꯔꯥꯏꯗ ꯴ ꯑꯁꯤ ꯅ꯭ꯌꯨꯛꯂꯤꯑꯣꯐꯥꯏꯜ ꯑꯃꯒꯥ (ꯈꯨꯗꯝ ꯑꯣꯏꯅꯥ, ꯏꯊꯥꯏꯂꯃꯥꯏꯟ, ꯴-ꯇꯣꯂꯨꯏꯗꯤꯟ, ꯑꯃꯁꯨꯡ ꯴-ꯃꯦꯊꯣꯛꯁꯤꯑꯦꯅꯤꯂꯤꯟ) ꯗꯥꯏꯑꯣꯛꯁꯦꯅꯗꯥ ꯁꯣꯂꯚꯦꯟꯇ ꯑꯣꯏꯅꯥ ꯑꯃꯁꯨꯡ ꯇꯤ.ꯏ.ꯑꯦ.ꯅꯥ ꯀꯦꯇꯥꯂꯤꯁ꯭ꯠ ꯑꯃꯥ ꯑꯣꯏꯅꯥ ꯔꯨꯝ ꯇꯦꯝꯄꯦꯔꯦꯆꯔꯗꯥ ꯔꯤꯑꯦꯛꯁꯟ ꯇꯧꯕꯅꯥ ꯒ꯭ꯔꯤꯟ ꯀ꯭ꯔꯤꯁ꯭ꯇꯦꯂꯥꯏꯟ ꯑꯦꯛꯔꯤꯂꯥꯃꯥꯏꯗ ꯗꯦꯔꯤꯕꯦꯇꯤꯕ ꯱꯸, ꯱꯹ꯑꯦ, ꯑꯃꯁꯨꯡ ꯱꯹ꯕꯤ ꯄꯤꯈꯤ꯫ ꯀꯝꯄꯥꯎꯟꯗ ꯱꯸, ꯱꯹ꯑꯦ, ꯑꯃꯁꯨꯡ ꯱꯹ꯕꯤꯒꯤ ꯏꯂꯤꯃꯦꯟꯇꯔꯤ ꯑꯃꯁꯨꯡ ꯁ꯭ꯄꯦꯛꯠꯔꯜ ꯗꯦꯇꯥꯅꯥ ꯍꯥꯌꯔꯤꯕꯥ ꯗꯦꯔꯤꯕꯦꯇꯤꯕꯁꯤꯡ ꯑꯁꯤꯒꯤ ꯁ꯭ꯠꯔꯀꯆꯔꯁꯤꯡ ꯑꯁꯤ ꯀꯅꯐꯔꯝ ꯇꯧꯈꯤ (ꯑꯦꯛꯁꯄꯤꯔꯤꯃꯦꯟꯇ ꯁꯦꯛꯁꯟ ꯌꯦꯡꯕꯤꯌꯨ) (ꯆꯤꯠꯔ ꯷)꯫
ꯇꯣꯉꯥꯟ ꯇꯣꯉꯥꯅꯕꯥ ꯁꯤꯟꯊꯦꯇꯤꯛ ꯀꯝꯄꯥꯎꯟꯗꯁꯤꯡꯒꯤ ꯑꯦꯟꯇꯤꯃꯥꯏꯛꯔꯣꯕꯤꯌꯥꯜ ꯑꯦꯛꯇꯤꯚꯤꯇꯤ ꯁ꯭ꯛꯔꯤꯟ ꯇꯧꯔꯕꯥ ꯃꯇꯨꯡꯗꯥ ꯇꯦꯕꯜ ꯱ ꯑꯃꯁꯨꯡ ꯐꯤꯒꯔ ꯸ꯗꯥ ꯎꯠꯂꯤꯕꯥ ꯃꯇꯨꯡ ꯏꯟꯅꯥ ꯇꯣꯉꯥꯟ ꯇꯣꯉꯥꯅꯕꯥ ꯔꯤꯖꯜꯇꯁꯤꯡ ꯐꯪꯈꯤ (ꯐꯤꯒꯔ ꯐꯥꯏꯜ ꯌꯦꯡꯕꯤꯌꯨ)꯫ ꯇꯦꯁ꯭ꯠ ꯇꯧꯈꯤꯕꯥ ꯀꯝꯄꯥꯎꯟꯗ ꯄꯨꯝꯅꯃꯛꯅꯥ ꯒ꯭ꯔꯥꯝ-ꯄꯣꯖꯤꯇꯤꯕ ꯕꯦꯛꯇꯦꯔꯤꯌꯥ ꯑꯦꯝ.ꯑꯥꯔ.ꯑꯦꯁ.ꯑꯦ.ꯒꯤ ꯃꯥꯌꯣꯛꯇꯥ ꯇꯣꯉꯥꯟ ꯇꯣꯉꯥꯅꯕꯥ ꯗꯤꯒ꯭ꯔꯤꯒꯤ ꯏꯅꯍꯤꯕꯤꯁꯟ ꯎꯠꯈꯤ, ꯑꯗꯨꯒꯥ ꯒ꯭ꯔꯥꯝ-ꯅꯦꯒꯦꯇꯤꯕ ꯕꯦꯛꯇꯦꯔꯤꯌꯥ ꯑꯦꯁ꯭ꯀꯦꯔꯤꯆꯤꯌꯥ ꯀꯣꯂꯤꯅꯥ ꯀꯝꯄꯣꯅꯦꯟꯇ ꯄꯨꯝꯅꯃꯛꯇꯥ ꯃꯄꯨꯡ ꯐꯥꯅꯥ ꯔꯦꯁꯤꯁ꯭ꯇꯦꯟꯁ ꯎꯠꯈꯤ꯫ ꯇꯦꯁ꯭ꯠ ꯇꯧꯈꯤꯕꯥ ꯀꯝꯄꯥꯎꯟꯗꯁꯤꯡ ꯑꯁꯤ ꯑꯦꯝ.ꯑꯥꯔ.ꯑꯦꯁ.ꯑꯦ.ꯒꯤ ꯃꯥꯌꯣꯛꯇꯥ ꯏꯅꯍꯤꯕꯤꯁꯟ ꯖꯣꯅꯒꯤ ꯗꯥꯏꯃꯦꯠꯔꯤꯀꯇꯥ ꯌꯨꯝꯐꯝ ꯑꯣꯏꯔꯒꯥ ꯀꯦꯇꯦꯒꯣꯔꯤ ꯑꯍꯨꯃꯗꯥ ꯈꯥꯌꯗꯣꯀꯄꯥ ꯌꯥꯏ꯫ ꯑꯍꯥꯅꯕꯥ ꯀꯦꯇꯦꯒꯣꯔꯤ ꯑꯁꯤ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯑꯦꯛꯇꯤꯕ ꯑꯣꯏꯈꯤ ꯑꯃꯁꯨꯡ ꯃꯁꯤꯗꯥ ꯀꯝꯄꯥꯎꯟꯗ ꯃꯉꯥ (꯶, ꯷, ꯱꯰, ꯱꯳ꯕꯤ ꯑꯃꯁꯨꯡ ꯱꯴) ꯌꯥꯑꯣꯈꯤ꯫ ꯀꯝꯄꯣꯅꯦꯟꯇꯁꯤꯡ ꯑꯁꯤꯒꯤ ꯏꯅꯍꯤꯕꯤꯁꯟ ꯖꯣꯅꯒꯤ ꯗꯥꯏꯃꯦꯠꯔꯤꯛ ꯑꯁꯤ ꯁꯦꯟꯇꯤꯃꯤꯇꯔ ꯴ꯒꯥ ꯅꯛꯅꯅꯥ ꯂꯩꯈꯤ; ꯀꯦꯇꯦꯒꯣꯔꯤ ꯑꯁꯤꯗꯥ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯑꯦꯛꯇꯤꯕ ꯑꯣꯏꯕꯥ ꯀꯝꯄꯣꯅꯦꯟꯇꯁꯤꯡꯗꯤ ꯀꯝꯄꯥꯎꯟꯗ ꯶ ꯑꯃꯁꯨꯡ ꯱꯳ꯕꯤꯅꯤ꯫ ꯑꯅꯤꯁꯨꯕꯥ ꯀꯦꯇꯦꯒꯣꯔꯤ ꯑꯁꯤ ꯃꯌꯥꯌ ꯑꯣꯏꯕꯥ ꯑꯦꯛꯇꯤꯕ ꯑꯣꯏꯈꯤ ꯑꯃꯁꯨꯡ ꯃꯁꯤꯗꯥ ꯑꯇꯣꯞꯄꯥ ꯀꯝꯄꯥꯎꯟꯗ ꯃꯉꯥ (꯱꯱, ꯱꯳ꯑꯦ, ꯱꯵, ꯱꯸ ꯑꯃꯁꯨꯡ ꯱꯹ꯑꯦ) ꯌꯥꯑꯣꯈꯤ꯫ ꯍꯥꯌꯔꯤꯕꯥ ꯀꯝꯄꯣꯅꯦꯟꯇꯁꯤꯡ ꯑꯁꯤꯒꯤ ꯏꯅꯍꯤꯕꯤꯁꯟ ꯖꯣꯟ ꯑꯁꯤ ꯁꯦꯟꯇꯤꯃꯤꯇꯔ ꯳.꯳ꯗꯒꯤ ꯳.꯶꯵ ꯐꯥꯑꯣꯕꯥ ꯑꯣꯏꯈꯤ, ꯃꯁꯤꯗꯥ ꯀꯝꯄꯥꯎꯟꯗ ꯱꯱ꯅꯥ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯆꯥꯎꯕꯥ ꯏꯅꯍꯤꯕꯤꯁꯟ ꯖꯣꯟ ꯑꯁꯤ ꯁꯦꯟꯇꯤꯃꯤꯇꯔ ꯳.꯶꯵ ± ꯰.꯱ ꯎꯠꯈꯤ꯫ ꯑꯃꯔꯣꯃꯗꯥ, ꯑꯔꯣꯏꯕꯥ ꯀꯥꯡꯂꯨꯞ ꯑꯁꯤꯗꯥ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯅꯦꯝꯕꯥ ꯑꯦꯟꯇꯤꯃꯥꯏꯛꯔꯣꯕꯤꯌꯥꯜ ꯑꯦꯛꯇꯤꯚꯤꯇꯤ (ꯁꯦ.ꯃꯤ. ꯳ꯗꯒꯤ ꯇꯥꯕꯥ) ꯂꯩꯕꯥ ꯀꯝꯄꯥꯎꯟꯗ ꯑꯍꯨꯝ (꯸, ꯱꯷ ꯑꯃꯁꯨꯡ ꯱꯹ꯕꯤ) ꯌꯥꯑꯣꯈꯤ꯫ ꯐꯤꯒꯔ ꯹ꯅꯥ ꯇꯣꯉꯥꯟ ꯇꯣꯉꯥꯅꯕꯥ ꯏꯅꯍꯤꯕꯤꯁꯟ ꯖꯣꯅꯁꯤꯡꯒꯤ ꯌꯦꯟꯊꯣꯀꯄꯒꯤ ꯃꯑꯣꯡ ꯑꯗꯨ ꯎꯠꯂꯤ꯫
ꯇꯦꯁ꯭ꯠ ꯇꯧꯈꯤꯕꯥ ꯀꯝꯄꯣꯅꯦꯟꯇꯁꯤꯡꯒꯤ ꯑꯦꯟꯇꯤꯃꯥꯏꯛꯔꯣꯕꯤꯌꯥꯜ ꯑꯦꯛꯇꯤꯚꯤꯇꯤꯒꯤ ꯃꯇꯥꯡꯗꯥ ꯃꯈꯥ ꯇꯥꯅꯥ ꯊꯤꯖꯤꯅꯕꯗꯥ ꯀꯝꯄꯣꯅꯦꯟꯇ ꯈꯨꯗꯤꯡꯃꯛꯀꯤ ꯑꯦꯝ.ꯑꯥꯏ.ꯁꯤ. ꯑꯃꯁꯨꯡ ꯑꯦꯝ.ꯕꯤ.ꯁꯤ. ꯔꯤꯖꯜꯇꯁꯤꯡ ꯑꯁꯤ ꯈꯔꯥ ꯈꯦꯠꯅꯈꯤ (ꯇꯦꯕꯜ ꯲, ꯳ ꯑꯃꯁꯨꯡ ꯐꯤꯒꯔ ꯱꯰ꯗꯥ ꯎꯠꯂꯤꯕꯥ ꯃꯇꯨꯡ ꯏꯟꯅꯥ (ꯐꯤꯒꯔ ꯐꯥꯏꯜ ꯌꯦꯡꯕꯤꯌꯨ)), ꯀꯝꯄꯥꯎꯟꯗ ꯷, ꯱꯱, ꯱꯳ꯑꯦ ꯑꯃꯁꯨꯡ ꯱꯵ ꯑꯁꯤ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯐꯕꯥ ꯀꯝꯄꯥꯎꯟꯗ ꯑꯣꯏꯅꯥ ꯑꯃꯨꯛ ꯍꯟꯅꯥ ꯀ꯭ꯂꯥꯁꯤꯐꯥꯏ ꯇꯧꯈꯤ ꯍꯥꯌꯅꯥ ꯂꯧꯅꯩ꯫ ꯃꯈꯣꯌꯒꯤ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯅꯦꯝꯕꯥ ꯑꯦꯝ.ꯑꯥꯏ.ꯁꯤ. ꯑꯃꯁꯨꯡ ꯑꯦꯝ.ꯕꯤ.ꯁꯤ.ꯒꯤ ꯚꯦꯜꯌꯨꯁꯤꯡ (꯳꯹.꯰꯶ μg/꯱꯰꯰ μL) ꯃꯥꯟꯅꯈꯤ꯫ ꯀꯝꯄꯥꯎꯟꯗ ꯷ ꯑꯃꯁꯨꯡ ꯸ꯒꯤ ꯑꯦꯝ.ꯑꯥꯏ.ꯁꯤ.ꯒꯤ ꯚꯦꯜꯌꯨꯁꯤꯡ (꯹.꯷ μg/꯱꯰꯰ μL) ꯍꯦꯟꯅꯥ ꯅꯦꯝꯂꯕꯁꯨ, ꯃꯈꯣꯌꯒꯤ ꯑꯦꯝ.ꯕꯤ.ꯁꯤ.ꯒꯤ ꯚꯦꯜꯌꯨꯁꯤꯡꯗꯤ ꯍꯦꯟꯅꯥ ꯋꯥꯡꯈꯤ (꯷꯸.꯱꯲꯵ μg/꯱꯰꯰ μL)꯫ ꯃꯔꯝ ꯑꯗꯨꯅꯥ ꯃꯈꯣꯌ ꯑꯁꯤ ꯃꯃꯥꯡꯗꯥ ꯄꯅꯈꯤꯕꯥ ꯀꯝꯄꯥꯎꯟꯗꯁꯤꯡꯗꯒꯤ ꯍꯦꯟꯅꯥ ꯂꯨꯕꯥ ꯑꯣꯏꯅꯥ ꯂꯧꯅꯔꯝꯃꯤ꯫ ꯑꯗꯨꯝ ꯑꯣꯏꯅꯃꯛ, ꯍꯥꯌꯔꯤꯕꯥ ꯀꯝꯄꯣꯅꯦꯟꯇ ꯶ ꯑꯁꯤꯅꯥ ꯇꯦꯁ꯭ꯠ ꯇꯧꯈꯤꯕꯁꯤꯡ ꯑꯁꯤꯒꯤ ꯃꯅꯨꯡꯗꯥ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯏꯐꯦꯛꯇꯤꯕ ꯑꯣꯏꯈꯤ, ꯃꯔꯃꯗꯤ ꯃꯈꯣꯌꯒꯤ ꯑꯦꯝ.ꯕꯤ.ꯁꯤ.ꯒꯤ ꯚꯦꯜꯌꯨꯁꯤꯡ ꯑꯁꯤ ꯱꯰꯰ μg/꯱꯰꯰ μLꯒꯤ ꯃꯈꯥꯗꯥ ꯂꯩꯈꯤ꯫
ꯀꯝꯄꯣꯅꯦꯟꯇꯁꯤꯡ (꯱꯰, ꯱꯴, ꯱꯸ ꯑꯃꯁꯨꯡ ꯱꯹ꯕꯤ) ꯑꯁꯤ ꯑꯇꯣꯞꯄꯥ ꯇꯦꯁ꯭ꯠ ꯇꯧꯈꯤꯕꯥ ꯀꯝꯄꯥꯎꯟꯗꯁꯤꯡꯒꯥ ꯆꯥꯡꯗꯝꯅꯕꯗꯥ ꯑꯦꯛꯇꯤꯕ ꯑꯣꯏꯈꯤꯗꯦ ꯃꯔꯃꯗꯤ ꯃꯈꯣꯌꯒꯤ ꯑꯦꯝ.ꯕꯤ.ꯁꯤ. ꯑꯃꯔꯣꯃꯗꯥ, ꯀꯝꯄꯣꯅꯦꯟꯇꯁꯤꯡ (꯸, ꯱꯷ ꯑꯃꯁꯨꯡ ꯱꯹ꯑꯦ) ꯑꯁꯤ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯋꯥꯡꯕꯥ ꯑꯦꯝ.ꯕꯤ.ꯁꯤ.ꯒꯤ ꯚꯦꯜꯌꯨꯁꯤꯡ (ꯃꯊꯪꯁꯤꯠꯅꯥ ꯶꯲꯵, ꯶꯲꯵ ꯑꯃꯁꯨꯡ ꯱꯲꯵꯰ μg/꯱꯰꯰ μL) ꯂꯩꯕꯅꯥ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯌꯥꯝꯅꯥ ꯊꯥꯖꯅꯤꯡꯉꯥꯏ ꯑꯣꯏꯈꯤ꯫
ꯑꯔꯣꯏꯕꯗꯥ, ꯇꯦꯕꯜ ꯳ꯗꯥ ꯎꯠꯂꯤꯕꯥ ꯇꯣꯂꯦꯔꯦꯟꯁꯀꯤ ꯊꯥꯀꯁꯤꯡꯒꯤ ꯃꯇꯨꯡ ꯏꯟꯅꯥ, ꯇꯦꯁ꯭ꯠ ꯇꯧꯈꯤꯕꯥ ꯀꯝꯄꯣꯅꯦꯟꯇꯁꯤꯡ ꯑꯁꯤ ꯃꯈꯣꯌꯒꯤ ꯑꯦꯛꯁꯅꯒꯤ ꯃꯑꯣꯡ ꯃꯇꯧꯗꯥ ꯌꯨꯝꯐꯝ ꯑꯣꯏꯔꯒꯥ ꯀꯦꯇꯦꯒꯣꯔꯤ ꯑꯅꯤꯗꯥ ꯈꯥꯌꯗꯣꯀꯄꯥ ꯌꯥꯏ: ꯕꯦꯛꯇꯦꯔꯤꯁꯤꯗꯜ ꯏꯐꯦꯛꯇ ꯂꯩꯕꯥ ꯀꯝꯄꯥꯎꯟꯗꯁꯤꯡ (꯷, ꯸, ꯱꯰, ꯱꯱, ꯱꯳ꯑꯦ, ꯱꯵, ꯱꯸, ꯱꯹ꯕꯤ) ꯑꯃꯁꯨꯡ ꯑꯦꯟꯇꯤꯕꯦꯛꯇꯦꯔꯤꯑꯦꯜ ꯏꯐꯦꯛꯇ ꯂꯩꯕꯥ ꯀꯝꯄꯥꯎꯟꯗꯁꯤꯡ (꯶, ꯱꯳ꯕꯤ, ꯱꯴, ꯱꯷, ꯱꯹ꯑꯦ)꯫ ꯃꯈꯣꯌꯒꯤ ꯃꯅꯨꯡꯗꯥ, ꯀꯝꯄꯣꯅꯦꯟꯇ ꯷, ꯱꯱, ꯱꯳a ꯑꯃꯁꯨꯡ ꯱꯵ ꯑꯁꯤ ꯍꯦꯟꯅꯥ ꯄꯥꯝꯃꯤ, ꯃꯈꯣꯌꯁꯤꯡ ꯑꯁꯤꯅꯥ ꯌꯥꯝꯅꯥ ꯅꯦꯝꯕꯥ ꯀꯟꯁꯦꯟꯠꯔꯦꯁꯟ (꯳꯹.꯰꯶ μg/꯱꯰꯰ μL)ꯗꯥ ꯁꯤꯕꯒꯤ ꯊꯕꯛ ꯊꯧꯔꯝ ꯎꯠꯂꯤ꯫
ꯇꯦꯁ꯭ꯠ ꯇꯧꯈꯤꯕꯥ ꯀꯝꯄꯥꯎꯟꯗ ꯇꯔꯥꯒꯤ ꯃꯅꯨꯡꯗꯥ ꯱꯰ꯅꯥ ꯑꯦꯟꯇꯤꯕꯥꯏꯑꯣꯇꯤꯛ-ꯔꯦꯁꯤꯁ꯭ꯇꯦꯟꯇ ꯃꯦꯊꯤꯁꯤꯂꯤꯟ-ꯔꯦꯁꯤꯁ꯭ꯇꯦꯟꯇ ꯁ꯭ꯇꯥꯐꯥꯏꯂꯣꯀꯣꯀꯁ ꯑꯣꯔꯦꯁ (ꯑꯦꯝ.ꯑꯥꯔ.ꯑꯦꯁ.ꯑꯦ.)ꯒꯤ ꯃꯥꯌꯣꯛꯇꯥ ꯄꯣꯇꯦꯟꯁꯤꯌꯦꯜ ꯎꯠꯈꯤ꯫ ꯃꯔꯝ ꯑꯁꯤꯅꯥ, ꯍꯦꯟꯅꯥ ꯑꯦꯟꯇꯤꯕꯥꯏꯑꯣꯇꯤꯛ-ꯔꯦꯁꯤꯁ꯭ꯇꯦꯟꯇ ꯄꯦꯊꯣꯖꯦꯅꯁꯤꯡ (ꯃꯔꯨꯑꯣꯏꯅꯥ ꯄꯦꯊꯣꯖꯦꯅꯤꯛ ꯒ꯭ꯔꯥꯝ-ꯄꯣꯖꯤꯇꯤꯕ ꯑꯃꯁꯨꯡ ꯒ꯭ꯔꯥꯝ-ꯅꯦꯒꯦꯇꯤꯕ ꯕꯦꯛꯇꯦꯔꯤꯌꯥ ꯀꯚꯔ ꯇꯧꯕꯥ ꯂꯣꯀꯦꯜ ꯑꯥꯏꯁꯣꯂꯦꯠꯁꯤꯡ) ꯑꯃꯁꯨꯡ ꯄꯦꯊꯣꯖꯦꯅꯤꯛ ꯌꯦꯠꯁꯤꯡꯒꯥ ꯂꯣꯌꯅꯅꯥ ꯃꯈꯥ ꯇꯥꯅꯥ ꯁ꯭ꯛꯔꯤꯅꯤꯡ ꯇꯧꯕꯥ, ꯃꯁꯤꯒꯥ ꯂꯣꯌꯅꯅꯥ ꯃꯁꯤꯒꯤ ꯁꯦꯐꯇꯤ ꯑꯁꯤ ꯌꯦꯡꯁꯤꯟꯅꯕꯥ ꯀꯝꯄꯥꯎꯟꯗ ꯈꯨꯗꯤꯡꯃꯛꯀꯤ ꯁꯥꯏꯇꯣꯇꯣꯛꯁꯤꯛ ꯇꯦꯁ꯭ꯠ ꯇꯧꯕꯥ ꯑꯁꯤ ꯇꯀꯁꯤꯜꯂꯤ꯫
ꯃꯣꯂꯤꯛꯌꯨꯂꯔ ꯗꯣꯀꯤꯡ ꯁ꯭ꯇꯗꯤꯁꯤꯡ ꯑꯁꯤ ꯃꯦꯊꯤꯁꯤꯂꯤꯟ-ꯔꯦꯁꯤꯁ꯭ꯇꯦꯟꯇ ꯁ꯭ꯇꯥꯐꯥꯏꯂꯣꯀꯣꯀꯁ ꯑꯣꯔꯦꯁ (ꯑꯦꯝ.ꯑꯥꯔ.ꯑꯦꯁ.ꯑꯦ.)ꯗꯥ ꯄꯦꯅꯤꯁꯤꯂꯤꯟ-ꯕꯥꯏꯟꯗꯤꯡ ꯄ꯭ꯔꯣꯇꯤꯟ ꯲ꯑꯦ (ꯄꯤ.ꯕꯤ.ꯄꯤ.꯲ꯑꯦ)ꯒꯤ ꯏꯅꯍꯤꯕꯤꯇꯔ ꯑꯣꯏꯅꯥ ꯁꯤꯟꯊꯦꯁꯤꯁ ꯇꯧꯔꯕꯥ ꯀꯝꯄꯥꯎꯟꯗꯁꯤꯡ ꯑꯁꯤꯒꯤ ꯄꯣꯇꯦꯟꯁꯤꯌꯦꯜ ꯑꯗꯨ ꯏꯚꯥꯂꯨꯑꯦꯠ ꯇꯧꯅꯕꯥ ꯄꯥꯡꯊꯣꯀꯈꯤ꯫ ꯄꯤ.ꯕꯤ.ꯄꯤ.꯲ꯑꯦ ꯑꯁꯤ ꯕꯦꯛꯇꯦꯔꯤꯌꯥ ꯁꯦꯜ ꯋꯥꯜ ꯕꯥꯏꯑꯣꯁꯤꯟꯊꯦꯁꯤꯁꯇꯥ ꯁꯔꯨꯛ ꯌꯥꯕꯥ ꯃꯔꯨꯑꯣꯏꯕꯥ ꯑꯦꯅꯖꯥꯏꯝ ꯑꯃꯅꯤ, ꯑꯃꯁꯨꯡ ꯑꯦꯅꯖꯥꯏꯝ ꯑꯁꯤ ꯊꯤꯡꯕꯅꯥ ꯁꯦꯜ ꯋꯥꯜ ꯁꯦꯝꯕꯗꯥ ꯑꯀꯥꯌꯕꯥ ꯄꯤ, ꯃꯁꯤꯅꯥ ꯑꯔꯣꯏꯕꯗꯥ ꯕꯦꯛꯇꯦꯔꯤꯌꯥ ꯂꯥꯏꯁꯤꯁ ꯑꯃꯁꯨꯡ ꯁꯦꯜ ꯁꯤꯍꯅꯕꯥ ꯊꯣꯀꯍꯜꯂꯤ1꯫ ꯗꯣꯀꯤꯡꯒꯤ ꯔꯤꯖꯜꯇꯁꯤꯡ ꯑꯁꯤ ꯇꯦꯕꯜ ꯴ꯗꯥ ꯂꯤꯁ꯭ꯠ ꯇꯧꯔꯤ ꯑꯃꯁꯨꯡ ꯁꯞꯂꯤꯃꯦꯟꯇꯔꯤ ꯗꯦꯇꯥ ꯐꯥꯏꯂꯗꯥ ꯍꯦꯟꯅꯥ ꯑꯀꯨꯞꯄꯥ ꯃꯔꯣꯂꯗꯥ ꯐꯣꯉꯗꯣꯛꯂꯤ, ꯑꯃꯁꯨꯡ ꯔꯤꯖꯜꯇꯁꯤꯡ ꯑꯁꯤꯅꯥ ꯇꯥꯛꯂꯤ ꯃꯗꯨꯗꯤ ꯀꯝꯄꯣꯅꯦꯟꯇ ꯀꯌꯥ ꯑꯃꯅꯥ ꯄꯤ.ꯕꯤ.ꯄꯤ.꯲ꯑꯦ.ꯒꯤꯗꯃꯛꯇꯥ ꯑꯀꯅꯕꯥ ꯕꯥꯏꯟꯗꯤꯡ ꯑꯦꯐꯤꯅꯤꯇꯤ ꯎꯠꯈꯤ, ꯃꯔꯨꯑꯣꯏꯅꯥ ꯂꯥꯏꯁ ꯲꯷꯳, ꯂꯥꯏꯁ ꯳꯱꯶, ꯑꯃꯁꯨꯡ ꯑꯥꯔꯒ ꯲꯹꯸ꯒꯨꯝꯕꯥ ꯃꯔꯨꯑꯣꯏꯕꯥ ꯑꯦꯛꯇꯤꯕ ꯁꯥꯏꯠ ꯔꯦꯁꯤꯗꯦꯟꯇꯁꯤꯡ, ꯍꯥꯏꯗ꯭ꯔꯣꯖꯦꯟ ꯕꯣꯟꯗꯤꯡ ꯑꯃꯁꯨꯡ π-ꯁ꯭ꯇꯦꯀꯤꯡ ꯌꯥꯑꯣꯅꯥ ꯏꯟꯇꯔꯦꯛꯁꯅꯁꯤꯡ ꯑꯁꯤ... ꯀꯣ-ꯀ꯭ꯔꯤꯁ꯭ꯇꯦꯂꯥꯏꯖ ꯇꯧꯔꯕꯥ ꯀꯨꯏꯅꯥꯖꯣꯂꯤꯅꯣꯟ ꯂꯤꯒꯦꯟꯗ (ꯁꯤ.ꯁꯤ.ꯑꯦꯜ.), ꯃꯁꯤꯅꯥ ꯀꯝꯄꯣꯅꯦꯟꯇꯁꯤꯡ ꯑꯁꯤꯒꯤ ꯄꯣꯇꯦꯟꯁꯤꯑꯦꯜ ꯑꯁꯤ ꯄꯣꯇꯦꯟꯇ ꯏꯅꯍꯤꯕꯤꯇꯔ ꯑꯣꯏꯅꯥ ꯇꯥꯛꯂꯤ꯫
ꯃꯣꯂꯤꯛꯌꯨꯂꯔ ꯗꯣꯀꯤꯡ ꯗꯦꯇꯥ ꯑꯁꯤꯅꯥ ꯑꯇꯣꯞꯄꯥ ꯀꯝꯞꯌꯨꯇꯦꯁ꯭ꯅꯦꯜ ꯄꯦꯔꯥꯃꯤꯇꯔꯁꯤꯡꯒꯥ ꯂꯣꯌꯅꯅꯥ ꯄꯤ.ꯕꯤ.ꯄꯤ.꯲ꯑꯦ. ꯗꯣꯀꯤꯡ ꯁ꯭ꯀꯣꯔꯁꯤꯡ ꯑꯃꯁꯨꯡ ꯔꯨꯠ ꯃꯤꯟ ꯁ꯭ꯛꯕꯥꯔ ꯗꯦꯕꯤꯌꯦꯁꯟ (ꯑꯥꯔ.ꯑꯦꯝ.ꯑꯦꯁ.ꯗꯤ.) ꯚꯦꯜꯌꯨꯁꯤꯡꯅꯥ ꯃꯈꯥ ꯇꯥꯅꯥ ꯕꯥꯏꯟꯗꯤꯡ ꯑꯦꯐꯤꯅꯤꯇꯤ ꯑꯃꯁꯨꯡ ꯁ꯭ꯇꯦꯕꯤꯂꯤꯇꯤ ꯐꯣꯡꯗꯣꯀꯈꯤ, ꯃꯁꯤꯅꯥ ꯍꯥꯌꯔꯤꯕꯥ ꯍꯥꯏꯄꯣꯇꯦꯁꯤꯁ ꯑꯁꯤꯕꯨ ꯃꯇꯦꯡ ꯄꯥꯡꯈꯤ꯫ ꯇꯦꯕꯜ ꯴ꯗꯥ ꯎꯠꯂꯤꯕꯥ ꯃꯇꯨꯡ ꯏꯟꯅꯥ, ꯀꯝꯄꯣꯅꯦꯟꯇ ꯀꯌꯥ ꯑꯃꯅꯥ ꯑꯐꯕꯥ ꯕꯥꯏꯟꯗꯤꯡ ꯑꯦꯐꯤꯅꯤꯇꯤ ꯎꯠꯂꯕꯁꯨ, ꯀꯝꯄꯣꯅꯦꯟꯇ ꯈꯔꯅꯥ (ꯈꯨꯗꯝ ꯑꯣꯏꯅꯥ, ꯷, ꯹, ꯱꯰, ꯑꯃꯁꯨꯡ ꯱꯴) ꯀꯣ-ꯀ꯭ꯔꯤꯁ꯭ꯇꯦꯂꯥꯏꯖ ꯇꯧꯔꯕꯥ ꯂꯤꯒꯦꯟꯗꯗꯒꯤ ꯍꯦꯟꯅꯥ ꯗꯣꯀꯤꯡ ꯁ꯭ꯀꯣꯔꯁꯤꯡ ꯂꯩꯈꯤ, ꯃꯁꯤꯅꯥ ꯃꯈꯣꯌꯅꯥ ꯄꯤ.ꯕꯤ.ꯄꯤ.꯲ꯑꯦ.ꯒꯤ ꯑꯦꯛꯇꯤꯕ ꯁꯥꯏꯠ ꯔꯦꯁꯤꯗꯦꯟꯇꯁꯤꯡꯒꯥ ꯍꯦꯟꯅꯥ ꯀꯅꯈꯠꯄꯥ ꯏꯟꯇꯔꯦꯛꯁꯟ ꯂꯩꯕꯥ ꯌꯥꯏ ꯍꯥꯌꯕꯥ ꯇꯥꯀꯏ꯫ ꯑꯗꯨꯝ ꯑꯣꯏꯅꯃꯛ, ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯕꯥꯏꯑꯣꯑꯦꯛꯇꯤꯕ ꯀꯝꯄꯣꯅꯦꯟꯇ ꯶ ꯑꯃꯁꯨꯡ ꯱꯳ꯕꯤꯅꯥ ꯑꯇꯣꯞꯄꯥ ꯂꯤꯒꯦꯟꯗꯁꯤꯡꯒꯥ ꯆꯥꯡꯗꯝꯅꯕꯗꯥ ꯈꯔꯥ ꯍꯦꯟꯅꯥ ꯅꯦꯝꯕꯥ ꯗꯣꯀꯤꯡ ꯁ꯭ꯀꯣꯔꯁꯤꯡ (ꯃꯊꯪꯁꯤꯠꯅꯥ -꯵.꯹꯸ ꯑꯃꯁꯨꯡ -꯵.꯶꯳) ꯎꯠꯈꯤ꯫ ꯃꯁꯤꯅꯥ ꯇꯥꯛꯂꯤ ꯃꯗꯨꯗꯤ ꯗꯣꯀꯤꯡ ꯁ꯭ꯀꯣꯔꯁꯤꯡ ꯑꯁꯤ ꯕꯥꯏꯟꯗꯤꯡ ꯑꯦꯐꯤꯅꯤꯇꯤ ꯂꯥꯎꯊꯣꯛꯅꯕꯥ ꯁꯤꯖꯤꯟꯅꯕꯥ ꯌꯥꯔꯕꯁꯨ, ꯑꯇꯣꯞꯄꯥ ꯐꯦꯛꯇꯔꯁꯤꯡ (ꯈꯨꯗꯝ ꯑꯣꯏꯅꯥ, ꯕꯥꯏꯑꯣꯂꯣꯖꯤꯀꯦꯜ ꯑꯦꯅꯚꯥꯏꯔꯅꯃꯦꯟꯇꯇꯥ ꯂꯤꯒꯦꯟꯗ ꯁ꯭ꯇꯦꯕꯤꯂꯤꯇꯤ ꯑꯃꯁꯨꯡ ꯃꯣꯂꯤꯛꯌꯨꯂꯔ ꯏꯟꯇꯔꯦꯛꯁꯅꯁꯤꯡ)ꯅꯁꯨ ꯑꯦꯟꯇꯤꯕꯦꯛꯇꯦꯔꯤꯑꯦꯜ ꯑꯦꯛꯇꯤꯚꯤꯇꯤ ꯂꯦꯄꯊꯣꯀꯄꯗꯥ ꯃꯔꯨꯑꯣꯏꯕꯥ ꯊꯧꯗꯥꯡ ꯂꯧꯔꯤ꯫ ꯊꯣꯏꯗꯣꯛ ꯍꯦꯟꯗꯣꯛꯅꯥ ꯄꯅꯒꯗꯕꯥ ꯑꯃꯅꯥ, ꯁꯤꯟꯊꯦꯁꯤꯁ ꯇꯧꯔꯕꯥ ꯀꯝꯄꯥꯎꯟꯗ ꯄꯨꯝꯅꯃꯛꯀꯤ ꯑꯥꯔ.ꯑꯦꯝ.ꯑꯦꯁ.ꯗꯤ.ꯒꯤ ꯚꯦꯜꯌꯨꯁꯤꯡ ꯑꯁꯤ ꯲ Åꯒꯤ ꯃꯈꯥꯗꯥ ꯂꯩꯈꯤ, ꯃꯁꯤꯅꯥ ꯃꯈꯣꯌꯒꯤ ꯗꯣꯀꯤꯡ ꯄꯣꯖꯁꯤꯡ ꯑꯁꯤ ꯀꯣ-ꯀ꯭ꯔꯤꯁ꯭ꯇꯦꯂꯥꯏꯖ ꯇꯧꯔꯕꯥ ꯂꯤꯒꯦꯟꯗꯒꯤ ꯕꯥꯏꯟꯗꯤꯡ ꯀꯟꯐꯣꯔꯃꯦꯁꯅꯒꯥ ꯁ꯭ꯠꯔꯀꯆꯔꯦꯜ ꯑꯣꯏꯅꯥ ꯃꯥꯟꯅꯩ ꯍꯥꯌꯕꯥ ꯀꯅꯐꯤꯗ ꯇꯧꯈꯤ, ꯃꯁꯤꯅꯥ ꯃꯈꯣꯌꯒꯤ ꯄꯣꯇꯦꯟꯁꯤꯌꯦꯜ ꯑꯁꯤ ꯄꯣꯇꯦꯟꯇ ꯄꯤ.ꯕꯤ.ꯄꯤ.꯲ꯑꯦ.
ꯗꯣꯀꯤꯡ ꯁ꯭ꯀꯣꯔꯁꯤꯡ ꯑꯃꯁꯨꯡ ꯑꯥꯔ.ꯑꯦꯝ.ꯑꯦꯁ.ꯀꯤ ꯚꯦꯜꯌꯨꯁꯤꯡꯅꯥ ꯃꯃꯜ ꯌꯥꯝꯂꯕꯥ ꯄ꯭ꯔꯤꯗꯤꯛꯁꯅꯁꯤꯡ ꯄꯤꯔꯕꯁꯨ, ꯗꯣꯀꯤꯡꯒꯤ ꯔꯤꯖꯜꯇꯁꯤꯡ ꯑꯁꯤ ꯑꯃꯁꯨꯡ ꯑꯦꯟꯇꯤꯃꯥꯏꯛꯔꯣꯕꯤꯌꯥꯜ ꯑꯦꯛꯇꯤꯚꯤꯇꯤꯒꯤ ꯃꯔꯛꯇꯥ ꯂꯩꯔꯤꯕꯥ ꯀꯣꯔꯤꯑꯦꯂꯦꯁꯟ ꯑꯁꯤ ꯑꯍꯥꯅꯕꯥ ꯃꯤꯠꯌꯦꯡꯗꯥ ꯃꯇꯝ ꯄꯨꯝꯅꯃꯛꯇꯥ ꯃꯌꯦꯛ ꯁꯦꯡꯗꯦ꯫ ꯄꯤ.ꯕꯤ.ꯄꯤ.꯲ꯑꯦ. ꯀꯝꯄꯣꯟꯗ ꯶ ꯑꯃꯁꯨꯡ ꯱꯳ꯕꯤꯅꯥ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯋꯥꯡꯕꯥ ꯑꯦꯟꯇꯤꯃꯥꯏꯛꯔꯣꯕꯤꯌꯥꯜ ꯑꯦꯛꯇꯤꯚꯤꯇꯤ ꯎꯠꯈꯤ, ꯃꯁꯤꯗꯥ ꯁꯦꯃꯤ ꯴ꯒꯤ ꯏꯅꯍꯤꯕꯤꯁꯟ ꯖꯣꯟ ꯗꯥꯏꯃꯦꯠꯔꯤꯛ ꯑꯃꯁꯨꯡ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯅꯦꯝꯕꯥ ꯑꯦꯝ.ꯑꯥꯏ.ꯁꯤ.(꯹.꯷ μg/꯱꯰꯰ μL) ꯑꯃꯁꯨꯡ ꯑꯦꯝ.ꯕꯤ.ꯁꯤ.(꯷꯸.꯱꯲꯵ μg/꯱꯰꯰ μL) ꯚꯦꯜꯌꯨ ꯑꯅꯤꯃꯛ ꯂꯩꯈꯤ, ꯃꯁꯤꯅꯥ ꯀꯝꯄꯣꯟꯗ ꯷, ꯹, ꯱꯰ ꯑꯃꯁꯨꯡ ꯱꯴ꯒꯥ ꯆꯥꯡꯗꯝꯅꯕꯗꯥ ꯃꯈꯣꯌꯒꯤ ꯗꯣꯀꯤꯡ ꯁ꯭ꯀꯣꯔꯁꯤꯡ ꯅꯦꯝꯅꯥ ꯂꯩꯔꯕꯁꯨ ꯃꯁꯤꯅꯥ ꯇꯥꯛꯂꯤ ꯃꯗꯨꯗꯤ ꯄꯤ.ꯕꯤ.ꯄꯤ.꯲ꯑꯦ ꯏꯅꯍꯤꯕꯤꯁꯟꯅꯥ ꯑꯦꯟꯇꯤꯃꯥꯏꯛꯔꯣꯕꯤꯌꯥꯜ ꯑꯦꯛꯇꯤꯚꯤꯇꯤꯗꯥ ꯃꯇꯦꯡ ꯄꯥꯡꯏ, ꯕꯦꯛꯇꯦꯔꯤꯌꯥꯒꯤ ꯑꯀꯣꯌꯕꯗꯥ ꯁꯣꯜꯌꯨꯕꯤꯂꯤꯇꯤ, ꯕꯥꯏꯑꯣꯑꯦꯕꯦꯂꯤꯕꯤꯂꯤꯇꯤ ꯑꯃꯁꯨꯡ ꯏꯟꯇꯔꯦꯛꯁꯟ ꯗꯥꯏꯅꯥꯃꯤꯀꯒꯨꯝꯕꯥ ꯐꯦꯛꯇꯔꯁꯤꯡꯅꯁꯨ ꯑꯄꯨꯅꯕꯥ ꯑꯦꯛꯇꯤꯚꯤꯇꯤꯗꯥ ꯁꯥꯐꯨ ꯄꯤ꯫ ꯐꯤꯒꯔ ꯱꯱ꯅꯥ ꯃꯈꯣꯌꯒꯤ ꯗꯣꯀꯤꯡ ꯄꯣꯖꯁꯤꯡ ꯎꯠꯂꯤ, ꯃꯁꯤꯅꯥ ꯇꯥꯛꯂꯤ ꯃꯗꯨꯗꯤ ꯀꯝꯄꯥꯎꯟꯗ ꯑꯅꯤꯃꯛ ꯑꯁꯤ, ꯌꯥꯝꯅꯥ ꯅꯦꯝꯕꯥ ꯕꯥꯏꯟꯗꯤꯡ ꯁ꯭ꯀꯣꯔꯁꯤꯡ ꯂꯩꯔꯕꯁꯨ, ꯍꯧꯖꯤꯀꯁꯨ ꯄꯤ.ꯕꯤ.ꯄꯤ.꯲ꯑꯦ.ꯒꯤ ꯃꯔꯨꯑꯣꯏꯕꯥ ꯔꯦꯁꯤꯗꯦꯟꯇꯁꯤꯡꯒꯥ ꯏꯟꯇꯔꯦꯛꯇ ꯇꯧꯕꯥ ꯉꯝꯃꯤ, ꯃꯁꯤꯅꯥ ꯏꯅꯍꯤꯕꯤꯁꯟ ꯀꯃꯞꯂꯦꯛꯁ ꯑꯁꯤ ꯁ꯭ꯇꯦꯕꯤꯂꯥꯏꯖ ꯇꯧꯕꯥ ꯉꯃꯒꯅꯤ꯫ ꯃꯁꯤꯅꯥ ꯇꯥꯛꯂꯤ ꯃꯗꯨꯗꯤ ꯃꯣꯂꯤꯛꯌꯨꯂꯔ ꯗꯣꯀꯤꯡꯅꯥ ꯄꯤ.ꯕꯤ.ꯄꯤ.꯲ꯑꯦ.
ꯄꯤ.ꯕꯤ.ꯄꯤ.꯲ꯑꯦ (ꯄꯤ.ꯗꯤ.ꯕꯤ. ꯑꯥꯏ.ꯗꯤ.: ꯴ꯁꯤ.ꯖꯦ.ꯑꯦꯟ.)ꯒꯤ ꯀ꯭ꯔꯤꯁ꯭ꯇꯦꯜ ꯁ꯭ꯠꯔꯀꯆꯔ ꯁꯤꯖꯤꯟꯅꯗꯨꯅꯥ ꯃꯦꯊꯤꯁꯤꯂꯤꯟ-ꯔꯦꯁꯤꯁ꯭ꯇꯦꯟꯇ ꯁ꯭ꯇꯥꯐꯥꯏꯂꯣꯀꯣꯀꯁ ꯑꯣꯔꯦꯁ (ꯑꯦꯝ.ꯑꯥꯔ.ꯑꯦꯁ.ꯑꯦ.)ꯒꯤ ꯄꯦꯅꯤꯁꯤꯂꯤꯟ-ꯕꯥꯏꯟꯗꯤꯡ ꯄ꯭ꯔꯣꯇꯤꯟ ꯲ꯑꯦ (ꯄꯤ.ꯕꯤ.ꯄꯤ.꯲ꯑꯦ)ꯒꯥ ꯂꯣꯌꯅꯅꯥ ꯗꯣꯛ ꯇꯧꯕꯥ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯑꯦꯛꯇꯤꯕ ꯀꯝꯄꯥꯎꯟꯗ ꯶ ꯑꯃꯁꯨꯡ ꯱꯳ꯕꯤꯒꯤ ꯲ꯗꯤ ꯑꯃꯁꯨꯡ ꯳ꯗꯤ ꯏꯟꯇꯔꯦꯛꯁꯟ ꯃꯦꯄꯁꯤꯡ ꯁꯦꯃꯈꯤ꯫ ꯃꯦꯄꯁꯤꯡ ꯑꯁꯤꯅꯥ ꯀꯝꯄꯣꯅꯦꯟꯇꯁꯤꯡ ꯑꯁꯤꯒꯤ ꯏꯟꯇꯔꯦꯛꯁꯟ ꯄꯦꯇꯔꯅꯁꯤꯡ ꯑꯁꯤ ꯔꯤ-ꯗꯣꯛ ꯇꯧꯔꯕꯥ ꯀꯣ-ꯀ꯭ꯔꯤꯁ꯭ꯇꯦꯂꯥꯏꯖ ꯇꯧꯔꯕꯥ ꯀꯨꯏꯅꯥꯖꯣꯂꯤꯅꯣꯟ ꯂꯤꯒꯦꯟꯗ (ꯁꯤ.ꯁꯤ.ꯑꯦꯜ.)ꯒꯥ ꯆꯥꯡꯗꯝꯅꯔꯤ, ꯃꯁꯤꯅꯥ ꯍꯥꯏꯗ꯭ꯔꯣꯖꯦꯟ ꯕꯣꯟꯗꯤꯡ, π-ꯁ꯭ꯇꯦꯀꯤꯡ, ꯑꯃꯁꯨꯡ ꯑꯥꯏꯑꯣꯅꯤꯛ ꯏꯟꯇꯔꯦꯛꯁꯅꯁꯤꯡꯒꯨꯝꯕꯥ ꯃꯔꯨꯑꯣꯏꯕꯥ ꯏꯟꯇꯔꯦꯛꯁꯅꯁꯤꯡ ꯐꯣꯉꯗꯣꯛꯂꯤ꯫
ꯀꯝꯄꯣꯁ꯭ꯠ ꯷ꯀꯤ ꯑꯣꯏꯅꯥ ꯃꯥꯟꯅꯕꯥ ꯃꯑꯣꯡ ꯑꯃꯥ ꯎꯕꯥ ꯐꯪꯈꯤ, ꯃꯁꯤꯅꯥ ꯀꯝꯄꯣꯁ꯭ꯠ ꯱꯰ꯒꯥ ꯃꯥꯟꯅꯕꯥ ꯏꯅꯍꯤꯕꯤꯁꯟ ꯖꯣꯟ ꯗꯥꯏꯃꯦꯠꯔꯤꯛ (-꯶.꯳꯲) ꯑꯃꯁꯨꯡ ꯃꯥꯟꯅꯕꯥ ꯏꯅꯍꯤꯕꯤꯁꯟ ꯖꯣꯟ ꯗꯥꯏꯃꯦꯠꯔꯤꯛ (ꯁꯦ.ꯃꯤ. ꯳.꯹) ꯎꯠꯈꯤ, ꯑꯗꯨꯝ ꯑꯣꯏꯅꯃꯛ ꯃꯁꯤꯒꯤ ꯑꯦꯝ.ꯑꯥꯏ.ꯁꯤ.(꯳꯹.꯰꯸ μg/꯱꯰꯰ μL) ꯑꯃꯁꯨꯡ ꯑꯦꯝ.ꯕꯤ.ꯁꯤ.(꯳꯹.꯰꯶ μg/꯱꯰꯰ μL) ꯑꯁꯤ ꯌꯥꯝꯅꯥ ꯋꯥꯡꯈꯤ, ꯃꯁꯤꯅꯥ ꯑꯦꯟꯇꯤꯕꯦꯛꯇꯦꯔꯤꯑꯦꯜ ꯏꯐꯦꯛꯇ ꯎꯠꯅꯕꯥ ꯍꯦꯟꯅꯥ ꯋꯥꯡꯕꯥ ꯀꯟꯁꯦꯟꯠꯔꯦꯁꯟ ꯃꯊꯧ ꯇꯥꯏ ꯍꯥꯌꯕꯥ ꯇꯥꯀꯏ꯫ ꯃꯁꯤꯅꯥ ꯇꯥꯛꯂꯤ ꯃꯗꯨꯗꯤ ꯀꯝꯄꯣꯁ꯭ꯠ ꯷ꯅꯥ ꯗꯣꯀꯤꯡ ꯁ꯭ꯇꯗꯤꯁꯤꯡꯗꯥ ꯑꯀꯅꯕꯥ ꯕꯥꯏꯟꯗꯤꯡ ꯑꯦꯐꯤꯅꯤꯇꯤ ꯎꯠꯂꯕꯁꯨ, ꯕꯥꯏꯑꯣꯑꯦꯕꯦꯂꯤꯕꯤꯂꯤꯇꯤ, ꯁꯦꯜꯌꯨꯂꯔ ꯑꯄꯇꯦꯛ, ꯅꯠꯠꯔꯒꯥ ꯑꯇꯣꯞꯄꯥ ꯐꯤꯖꯤꯀꯣꯀꯦꯃꯤꯀꯦꯜ ꯄ꯭ꯔꯣꯄꯔꯇꯤꯒꯨꯝꯕꯥ ꯐꯦꯛꯇꯔꯁꯤꯡꯅꯥ ꯃꯁꯤꯒꯤ ꯕꯥꯏꯑꯣꯂꯣꯖꯤꯀꯦꯜ ꯏꯐꯤꯁꯤꯑꯦꯟꯁꯤ ꯑꯁꯤ ꯂꯤꯃꯤꯠ ꯇꯧꯕꯥ ꯌꯥꯏ꯫ ꯀꯝꯄꯥꯎꯟꯗ ꯷ꯅꯥ ꯕꯦꯛꯇꯦꯔꯤꯌꯥ ꯁꯤꯗꯕꯒꯤ ꯃꯒꯨꯟ ꯎꯠꯂꯕꯁꯨ, ꯃꯁꯤꯅꯥ ꯀꯝꯄꯣꯁ꯭ꯠ ꯶ ꯑꯃꯁꯨꯡ ꯱꯳ꯕꯤꯒꯥ ꯆꯥꯡꯗꯝꯅꯕꯗꯥ ꯕꯦꯛꯇꯦꯔꯤꯌꯥ ꯍꯦꯅꯒꯠꯂꯀꯄꯥ ꯊꯤꯡꯕꯗꯥ ꯍꯦꯟꯅꯥ ꯏꯐꯦꯛꯇꯤꯕ ꯑꯣꯏꯈꯤ꯫
ꯀꯝꯄꯥꯎꯟꯗ ꯱꯰ꯅꯥ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯋꯥꯡꯕꯥ ꯗꯣꯀꯤꯡ ꯁ꯭ꯀꯣꯔ (-꯶.꯴꯰)ꯒꯥ ꯂꯣꯌꯅꯅꯥ ꯍꯦꯟꯅꯥ ꯅꯥꯠꯀꯤ ꯑꯣꯏꯕꯥ ꯈꯦꯠꯅꯕꯥ ꯑꯃꯥ ꯎꯠꯈꯤ, ꯃꯁꯤꯅꯥ ꯄꯤ.ꯕꯤ.ꯄꯤ.꯲ꯑꯦ.ꯗꯥ ꯑꯀꯅꯕꯥ ꯕꯥꯏꯟꯗꯤꯡ ꯑꯦꯐꯤꯅꯤꯇꯤ ꯎꯠꯈꯤ꯫ ꯑꯗꯨꯝ ꯑꯣꯏꯅꯃꯛ, ꯃꯁꯤꯒꯤ ꯖꯣꯟ ꯑꯣꯐ ꯏꯅꯍꯤꯕꯤꯁꯟ ꯗꯥꯏꯃꯦꯠꯔꯤꯛ (ꯁꯦ.ꯃꯤ. ꯳.꯹) ꯑꯁꯤ ꯀꯝꯄꯣꯁ꯭ꯠ ꯷ꯒꯥ ꯆꯥꯡꯗꯝꯅꯕꯥ ꯌꯥꯏ, ꯑꯃꯁꯨꯡ ꯃꯁꯤꯒꯤ ꯑꯦꯝ.ꯕꯤ.ꯁꯤ.(꯳꯱꯲ μg/꯱꯰꯰ μL) ꯑꯁꯤ ꯀꯝꯄꯣꯁ꯭ꯠ ꯶, ꯷, ꯑꯃꯁꯨꯡ ꯱꯳ꯕꯤꯗꯒꯤ ꯌꯥꯝꯅꯥ ꯋꯥꯡꯈꯤ, ꯃꯁꯤꯅꯥ ꯕꯦꯛꯇꯦꯔꯤꯁꯤꯗꯜ ꯑꯦꯛꯇꯤꯚꯤꯇꯤ ꯍꯦꯟꯅꯥ ꯂꯨꯕꯥ ꯍꯥꯌꯕꯥ ꯇꯥꯀꯏ꯫ ꯃꯁꯤꯅꯥ ꯇꯥꯛꯂꯤ ꯃꯗꯨꯗꯤ ꯑꯐꯕꯥ ꯗꯣꯀꯤꯡ ꯄ꯭ꯔꯤꯗꯤꯛꯁꯅꯁꯤꯡ ꯂꯩꯔꯕꯁꯨ, ꯀꯝꯄꯥꯎꯟꯗ ꯱꯰ ꯑꯁꯤ ꯁꯣꯜꯌꯨꯕꯤꯂꯤꯇꯤ, ꯁ꯭ꯇꯦꯕꯤꯂꯤꯇꯤ, ꯅꯠꯠꯔꯒꯥ ꯕꯦꯛꯇꯦꯔꯤꯌꯥꯒꯤ ꯃꯤꯠꯌꯦꯡꯗꯥ ꯌꯥꯝꯅꯥ ꯂꯨꯕꯥ ꯄꯔꯃꯤꯕꯤꯂꯤꯇꯤꯒꯨꯝꯕꯥ ꯑꯇꯣꯞꯄꯥ ꯂꯤꯃꯤꯇꯦꯗ ꯐꯦꯛꯇꯔꯁꯤꯡꯅꯥ ꯃꯔꯝ ꯑꯣꯏꯗꯨꯅꯥ ꯑꯦꯝ.ꯑꯥꯔ.ꯑꯦꯁ.ꯑꯦ. ꯃꯁꯤꯒꯤ ꯔꯤꯖꯜꯇꯁꯤꯡ ꯑꯁꯤꯅꯥ ꯄꯤ.ꯕꯤ.ꯄꯤ.꯲ꯑꯦ. ꯈꯦꯠꯅꯕꯁꯤꯡ ꯑꯁꯤꯅꯥ ꯇꯥꯛꯂꯤ ꯃꯗꯨꯗꯤ ꯃꯁꯤꯗꯥ ꯌꯥꯑꯣꯔꯤꯕꯥ ꯑꯦꯟꯇꯤꯕꯦꯛꯇꯦꯔꯤꯑꯦꯜ ꯃꯦꯀꯥꯅꯤꯖꯃꯁꯤꯡ ꯑꯁꯤ ꯃꯄꯨꯡ ꯐꯥꯅꯥ ꯈꯉꯗꯣꯛꯅꯕꯥ ꯃꯈꯥ ꯇꯥꯕꯥ ꯑꯦꯛꯁꯄꯤꯔꯤꯃꯦꯟꯇ ꯑꯦꯅꯥꯂꯥꯏꯁꯤꯁ ꯑꯃꯁꯨꯡ ꯏꯟ-ꯗꯦꯞ ꯕꯥꯏꯑꯣꯂꯣꯖꯤꯀꯦꯜ ꯏꯚꯥꯂꯨꯑꯦꯁꯅꯁꯤꯡ ꯃꯊꯧ ꯇꯥꯏ꯫
ꯇꯦꯕꯜ ꯴ ꯑꯃꯁꯨꯡ ꯁꯞꯂꯤꯃꯦꯟꯇꯔꯤ ꯗꯦꯇꯥ ꯐꯥꯏꯂꯗꯥ ꯄꯤꯔꯤꯕꯥ ꯃꯣꯂꯤꯛꯌꯨꯂꯔ ꯗꯣꯀꯤꯡꯒꯤ ꯔꯤꯖꯜꯇꯁꯤꯡ ꯑꯁꯤꯅꯥ ꯗꯣꯀꯤꯡ ꯁ꯭ꯀꯣꯔꯁꯤꯡ ꯑꯃꯁꯨꯡ ꯑꯦꯟꯇꯤꯃꯥꯏꯛꯔꯣꯕꯤꯌꯥꯜ ꯑꯦꯛꯇꯤꯚꯤꯇꯤꯒꯤ ꯃꯔꯛꯇꯥ ꯂꯩꯔꯤꯕꯥ ꯑꯔꯨꯕꯥ ꯃꯔꯤ ꯑꯗꯨ ꯐꯣꯡꯗꯣꯛꯂꯤ꯫ ꯀꯝꯄꯥꯎꯟꯗ ꯶ ꯑꯃꯁꯨꯡ ꯱꯳ꯕꯤꯅꯥ ꯀꯝꯄꯥꯎꯟꯗ ꯷, ꯹, ꯱꯰, ꯑꯃꯁꯨꯡ ꯱꯴ꯗꯒꯤ ꯍꯦꯟꯅꯥ ꯅꯦꯝꯕꯥ ꯗꯣꯀꯤꯡ ꯁ꯭ꯀꯣꯔ ꯂꯩꯔꯕꯁꯨ ꯃꯈꯣꯌꯅꯥ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯋꯥꯡꯕꯥ ꯑꯦꯟꯇꯤꯃꯥꯏꯛꯔꯣꯕꯤꯌꯥꯜ ꯑꯦꯛꯇꯤꯚꯤꯇꯤ ꯎꯠꯂꯤ꯫ ꯃꯈꯣꯌꯒꯤ ꯏꯟꯇꯔꯦꯛꯁꯟ ꯃꯦꯄꯁꯤꯡ (ꯐꯤꯒꯔ ꯱꯱ꯗꯥ ꯎꯠꯂꯤꯕꯥ) ꯑꯁꯤꯅꯥ ꯇꯥꯛꯂꯤ ꯃꯗꯨꯗꯤ ꯃꯈꯣꯌꯒꯤ ꯕꯥꯏꯟꯗꯤꯡ ꯁ꯭ꯀꯣꯔꯁꯤꯡ ꯑꯁꯤ ꯅꯦꯝꯅꯥ ꯂꯩꯔꯕꯁꯨ, ꯃꯈꯣꯌꯅꯥ ꯍꯧꯖꯤꯀꯁꯨ ꯃꯔꯨꯑꯣꯏꯕꯥ ꯍꯥꯏꯗ꯭ꯔꯣꯖꯦꯟ ꯕꯣꯟꯗꯁꯤꯡ ꯑꯃꯁꯨꯡ π-ꯁ꯭ꯇꯦꯀꯤꯡ ꯏꯟꯇꯔꯦꯛꯁꯅꯁꯤꯡ ꯁꯦꯃꯒꯠꯂꯤ ꯑꯃꯁꯨꯡ ꯃꯁꯤꯅꯥ ꯑꯦꯅꯖꯥꯏꯝ-ꯏꯅꯍꯤꯕꯤꯇꯔ ꯀꯃꯞꯂꯦꯛꯁ ꯑꯁꯤ ꯕꯥꯏꯑꯣꯂꯣꯖꯤꯀꯦꯜ ꯑꯣꯏꯅꯥ ꯀꯥꯟꯅꯕꯥ ꯃꯑꯣꯡꯗꯥ ꯁ꯭ꯇꯦꯕꯤꯂꯥꯏꯖ ꯇꯧꯕꯥ ꯉꯝꯃꯤ꯫ ꯶ ꯑꯃꯁꯨꯡ ꯱꯳ꯕꯤꯒꯤ ꯗꯣꯀꯤꯡ ꯁ꯭ꯀꯣꯔꯁꯤꯡ ꯑꯁꯤ ꯌꯥꯝꯅꯥ ꯅꯦꯝꯂꯕꯁꯨ, ꯃꯈꯣꯌꯒꯤ ꯍꯦꯅꯒꯠꯂꯛꯂꯤꯕꯥ ꯑꯦꯟꯇꯤꯃꯥꯏꯛꯔꯣꯕꯤꯌꯥꯜ ꯑꯦꯛꯇꯤꯚꯤꯇꯤ ꯑꯁꯤꯅꯥ ꯇꯥꯛꯂꯤ ꯃꯗꯨꯗꯤ ꯏꯅꯍꯤꯕꯤꯇꯔ ꯄꯣꯇꯦꯟꯁꯤꯑꯦꯜ ꯑꯁꯤ ꯑꯦꯁꯦꯁ ꯇꯧꯕꯥ ꯃꯇꯃꯗꯥ ꯁꯣꯜꯌꯨꯕꯤꯂꯤꯇꯤ, ꯁ꯭ꯇꯦꯕꯤꯂꯤꯇꯤ, ꯑꯃꯁꯨꯡ ꯁꯦꯜꯌꯨꯂꯔ ꯑꯄꯇꯦꯀꯒꯨꯝꯕꯥ ꯑꯇꯣꯞꯄꯥ ꯃꯒꯨꯅꯁꯤꯡ ꯑꯁꯤ ꯗꯣꯀꯤꯡ ꯗꯦꯇꯥꯒꯥ ꯂꯣꯌꯅꯅꯥ ꯈꯟꯅꯒꯗꯕꯅꯤ꯫ ꯃꯁꯤꯅꯥ ꯑꯅꯧꯕꯥ ꯀꯝꯄꯥꯎꯟꯗꯁꯤꯡꯒꯤ ꯊꯦꯔꯥꯞꯌꯨꯇꯤꯛ ꯄꯣꯇꯦꯟꯁꯤꯌꯦꯜ ꯑꯗꯨ ꯑꯆꯨꯝꯕꯥ ꯃꯑꯣꯡꯗꯥ ꯌꯦꯡꯁꯤꯟꯅꯕꯥ ꯑꯦꯛꯁꯄꯤꯔꯤꯃꯦꯟꯇ ꯑꯦꯟꯇꯤꯃꯥꯏꯛꯔꯣꯕꯤꯌꯥꯜ ꯑꯦꯅꯥꯂꯥꯏꯁꯤꯁꯀꯥ ꯂꯣꯌꯅꯅꯥ ꯗꯣꯀꯤꯡ ꯁ꯭ꯇꯗꯤꯁꯤꯡ ꯄꯨꯅꯁꯤꯟꯅꯕꯒꯤ ꯃꯔꯨꯑꯣꯏꯕꯥ ꯑꯗꯨ ꯐꯣꯡꯗꯣꯛꯂꯤ꯫
ꯃꯁꯤꯒꯤ ꯔꯤꯖꯜꯇꯁꯤꯡ ꯑꯁꯤꯅꯥ ꯃꯣꯂꯤꯛꯌꯨꯂꯔ ꯗꯣꯀꯤꯡ ꯑꯁꯤ ꯕꯥꯏꯟꯗꯤꯡ ꯑꯦꯐꯤꯅꯤꯇꯤ ꯂꯥꯎꯊꯣꯛꯅꯕꯥ ꯑꯃꯁꯨꯡ ꯏꯅꯍꯤꯕꯤꯁꯅꯒꯤ ꯑꯣꯏꯊꯣꯀꯄꯥ ꯌꯥꯕꯥ ꯃꯦꯀꯥꯅꯤꯖꯃꯁꯤꯡ ꯈꯉꯗꯣꯛꯅꯕꯥ ꯁꯛꯇꯤ ꯂꯩꯕꯥ ꯈꯨꯠꯂꯥꯌ ꯑꯃꯥ ꯑꯣꯏꯔꯕꯁꯨ, ꯑꯦꯟꯇꯤꯃꯥꯏꯛꯔꯣꯕꯤꯌꯥꯜ ꯏꯐꯤꯁꯤꯑꯦꯟꯁꯤ ꯂꯦꯄꯊꯣꯛꯅꯕꯥ ꯃꯁꯤ ꯈꯛꯇꯗꯥ ꯊꯥꯖꯕꯥ ꯊꯃꯒꯗꯕꯅꯤ ꯍꯥꯌꯕꯁꯤ ꯐꯣꯡꯗꯣꯛꯂꯤ꯫ ꯃꯣꯂꯤꯛꯌꯨꯂꯔ ꯗꯦꯇꯥ ꯑꯁꯤꯅꯥ ꯄꯤ.ꯕꯤ.ꯄꯤ.꯲ꯑꯦ. ꯇꯨꯡꯒꯤ ꯁ꯭ꯇꯗꯤꯁꯤꯡꯅꯥ ꯕꯥꯏꯑꯣꯑꯦꯕꯦꯂꯤꯕꯤꯂꯤꯇꯤ ꯑꯃꯁꯨꯡ ꯁꯦꯜꯌꯨꯂꯔ ꯑꯄꯇꯦꯛ ꯐꯒꯠꯍꯟꯅꯕꯥ ꯀꯝꯄꯥꯎꯟꯗ ꯷ ꯑꯃꯁꯨꯡ ꯱꯰ꯒꯤ ꯀꯦꯃꯤꯀꯦꯜ ꯁ꯭ꯠꯔꯀꯆꯔ ꯑꯁꯤ ꯑꯣꯞꯇꯤꯃꯥꯏꯖ ꯇꯧꯕꯗꯥ ꯃꯤꯠꯌꯦꯡ ꯊꯃꯒꯗꯕꯅꯤ, ꯃꯁꯤꯅꯥ ꯑꯆꯦꯠꯄꯥ ꯗꯣꯀꯤꯡ ꯏꯟꯇꯔꯦꯛꯁꯅꯁꯤꯡ ꯑꯁꯤ ꯇꯁꯦꯡꯕꯥ ꯑꯦꯟꯇꯤꯃꯥꯏꯛꯔꯣꯕꯤꯌꯥꯜ ꯑꯦꯛꯇꯤꯚꯤꯇꯤꯗꯥ ꯑꯣꯟꯊꯣꯀꯄꯥ ꯉꯃꯍꯅꯒꯅꯤ꯫ ꯑꯍꯦꯅꯕꯥ ꯕꯥꯏꯑꯣꯑꯦꯁꯦꯁ ꯑꯃꯁꯨꯡ ꯁ꯭ꯠꯔꯀꯆꯔ-ꯑꯦꯛꯇꯤꯕꯤꯇꯤ ꯔꯤꯂꯦꯁꯅꯁꯤꯞ (ꯑꯦꯁ.ꯑꯦ.ꯑꯥꯔ.) ꯑꯦꯅꯥꯂꯥꯏꯁꯤꯁ ꯌꯥꯑꯣꯅꯥ ꯃꯈꯥ ꯇꯥꯕꯥ ꯁ꯭ꯇꯗꯤꯁꯤꯡ ꯑꯁꯤꯅꯥ ꯀꯝꯄꯥꯎꯟꯗꯁꯤꯡ ꯑꯁꯤꯅꯥ ꯄꯤ.ꯕꯤ.ꯄꯤ.꯲ꯑꯦ.
꯳-(ꯑꯦꯟꯊ꯭ꯔꯥꯁꯦꯟ-꯹-ꯏꯜ)-꯲-ꯁꯥꯏꯅꯣꯑꯦꯛꯔꯤꯂꯣꯏꯜ ꯀ꯭ꯂꯣꯔꯥꯏꯗ ꯴ꯗꯒꯤ ꯁꯤꯟꯊꯦꯁꯤꯁ ꯇꯧꯕꯥ ꯀꯝꯄꯣꯅꯦꯟꯇꯁꯤꯡꯅꯥ ꯇꯣꯉꯥꯟ ꯇꯣꯉꯥꯅꯕꯥ ꯗꯤꯒ꯭ꯔꯤꯒꯤ ꯑꯦꯟꯇꯤꯃꯥꯏꯛꯔꯣꯕꯤꯌꯥꯜ ꯑꯦꯛꯇꯤꯚꯤꯇꯤ ꯎꯠꯈꯤ, ꯃꯁꯤꯗꯥ ꯀꯝꯄꯣꯅꯦꯟꯇ ꯀꯌꯥ ꯑꯃꯅꯥ ꯃꯦꯊꯤꯁꯤꯂꯤꯟ-ꯔꯦꯁꯤꯁ꯭ꯇꯦꯟꯇ ꯁ꯭ꯇꯥꯐꯥꯏꯂꯣꯀꯣꯀꯁ ꯑꯣꯔꯦꯁ (ꯑꯦꯝ.ꯑꯥꯔ.ꯑꯦꯁ.ꯑꯦ.)ꯗꯥ ꯃꯁꯛ ꯊꯣꯀꯄꯥ ꯏꯅꯍꯤꯕꯤꯁꯟ ꯎꯠꯈꯤ꯫ ꯁ꯭ꯠꯔꯀꯆꯔ-ꯑꯦꯛꯇꯤꯕꯤꯇꯤ ꯔꯤꯂꯦꯁꯅꯁꯤꯞ (ꯑꯦꯁ.ꯑꯦ.ꯑꯥꯔ.) ꯑꯦꯅꯥꯂꯥꯏꯁꯤꯁꯅꯥ ꯀꯝꯄꯣꯅꯦꯟꯇꯁꯤꯡ ꯑꯁꯤꯒꯤ ꯑꯦꯟꯇꯤꯃꯥꯏꯛꯔꯣꯕꯤꯌꯥꯜ ꯏꯐꯤꯁꯤꯑꯦꯟꯁꯤꯒꯤ ꯃꯈꯥ ꯄꯣꯜꯂꯤꯕꯥ ꯃꯔꯨꯑꯣꯏꯕꯥ ꯁ꯭ꯠꯔꯀꯆꯔꯦꯜ ꯐꯤꯆꯔꯁꯤꯡ ꯎꯕꯥ ꯐꯪꯈꯤ꯫
ꯑꯦꯛꯔꯤꯂꯣꯅꯥꯏꯠꯔꯥꯏꯜ ꯑꯃꯁꯨꯡ ꯑꯦꯟꯊ꯭ꯔꯥꯁꯤꯟ ꯀꯥꯡꯂꯨꯞ ꯑꯅꯤꯃꯛ ꯂꯩꯕꯥ ꯑꯁꯤ ꯑꯦꯟꯇꯤꯃꯥꯏꯛꯔꯣꯕꯤꯌꯥꯜ ꯑꯦꯛꯇꯤꯚꯤꯇꯤ ꯍꯦꯅꯒꯠꯍꯟꯅꯕꯒꯤꯗꯃꯛ ꯃꯔꯨꯑꯣꯏꯕꯥ ꯑꯃꯥ ꯑꯣꯏꯅꯥ ꯎꯠꯈꯤ꯫ ꯑꯦꯛꯔꯤꯂꯣꯅꯥꯏꯠꯔꯥꯏꯂꯗꯥ ꯂꯩꯕꯥ ꯌꯥꯝꯅꯥ ꯔꯤꯑꯦꯛꯇꯤꯕ ꯑꯣꯏꯕꯥ ꯅꯥꯏꯠꯔꯥꯏꯜ ꯒ꯭ꯔꯨꯞ ꯑꯁꯤ ꯕꯦꯛꯇꯦꯔꯤꯌꯥꯒꯤ ꯄ꯭ꯔꯣꯇꯤꯅꯁꯤꯡꯒꯥ ꯏꯟꯇꯔꯦꯛꯁꯟ ꯇꯧꯕꯗꯥ ꯂꯥꯏꯊꯣꯀꯍꯟꯅꯕꯥ ꯃꯊꯧ ꯇꯥꯏ, ꯃꯁꯤꯅꯥ ꯀꯝꯄꯣꯁ꯭ꯠ ꯑꯁꯤꯒꯤ ꯑꯦꯟꯇꯤꯃꯥꯏꯛꯔꯣꯕꯤꯌꯥꯜ ꯄ꯭ꯔꯣꯄꯔꯇꯤꯁꯤꯡꯗꯥ ꯃꯇꯦꯡ ꯄꯥꯡꯏ꯫ ꯑꯦꯛꯔꯤꯂꯣꯅꯥꯏꯠꯔꯥꯏꯜ ꯑꯃꯁꯨꯡ ꯑꯦꯟꯊ꯭ꯔꯥꯁꯤꯟ ꯑꯅꯤꯃꯛ ꯌꯥꯑꯣꯕꯥ ꯀꯝꯄꯥꯎꯟꯗꯁꯤꯡꯅꯥ ꯂꯦꯞꯇꯅꯥ ꯍꯦꯟꯅꯥ ꯀꯅꯕꯥ ꯑꯦꯟꯇꯤꯃꯥꯏꯛꯔꯣꯕꯤꯌꯥꯜ ꯏꯐꯦꯛꯇꯁꯤꯡ ꯎꯠꯈꯤ꯫ ꯑꯦꯟꯊ꯭ꯔꯥꯁꯤꯟ ꯀꯥꯡꯂꯨꯄꯀꯤ ꯑꯦꯔꯣꯃꯦꯇꯤꯁꯤꯇꯤꯅꯥ ꯀꯝꯄꯥꯎꯟꯗꯁꯤꯡ ꯑꯁꯤ ꯃꯈꯥ ꯇꯥꯅꯥ ꯁ꯭ꯇꯦꯕꯤꯂꯥꯏꯖ ꯇꯧꯈꯤ, ꯃꯁꯤꯅꯥ ꯃꯈꯣꯌꯒꯤ ꯕꯥꯏꯑꯣꯂꯣꯖꯤꯀꯦꯜ ꯑꯦꯛꯇꯤꯚꯤꯇꯤ ꯍꯦꯅꯒꯠꯍꯅꯕꯒꯤ ꯑꯣꯏꯊꯣꯀꯄꯥ ꯂꯩ꯫
ꯍꯦꯇꯦꯔꯣꯁꯥꯏꯛꯂꯤꯛ ꯔꯤꯡꯁꯤꯡ ꯁꯤꯖꯤꯟꯅꯕꯅꯥ ꯗꯦꯔꯤꯕꯦꯇꯤꯕ ꯀꯌꯥꯒꯤ ꯑꯦꯟꯇꯤꯕꯦꯛꯇꯦꯔꯤꯑꯦꯜ ꯏꯐꯤꯁꯤꯑꯦꯟꯁꯤꯗꯥ ꯌꯥꯝꯅꯥ ꯐꯒꯠꯍꯅꯈꯤ꯫ ꯃꯔꯨꯑꯣꯏꯅꯥ ꯕꯦꯟꯖꯣꯊꯤꯌꯥꯖꯣꯜ ꯗꯦꯔꯤꯕꯦꯇꯤꯕ ꯱꯳ꯕꯤ ꯑꯃꯁꯨꯡ ꯑꯦꯛꯔꯤꯂꯍꯥꯏꯗ꯭ꯔꯥꯖꯥꯏꯗ ꯗꯦꯔꯤꯕꯦꯇꯤꯕ ꯶ꯅꯥ ꯆꯥꯎꯔꯥꯛꯅꯥ ꯁꯦꯟꯇꯤꯃꯤꯇꯔ ꯴ꯒꯤ ꯏꯅꯍꯤꯕꯤꯁꯟ ꯖꯣꯟ ꯑꯃꯒꯥ ꯂꯣꯌꯅꯅꯥ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯋꯥꯡꯕꯥ ꯑꯦꯟꯇꯤꯕꯦꯛꯇꯦꯔꯤꯑꯦꯜ ꯑꯦꯛꯇꯤꯚꯤꯇꯤ ꯎꯠꯈꯤ꯫ ꯍꯥꯌꯔꯤꯕꯥ ꯍꯦꯇꯦꯔꯣꯁꯥꯏꯛꯂꯤꯛ ꯗꯦꯔꯤꯕꯦꯇꯤꯕꯁꯤꯡ ꯑꯁꯤꯅꯥ ꯍꯦꯟꯅꯥ ꯃꯔꯨ ꯑꯣꯏꯕꯥ ꯕꯥꯏꯑꯣꯂꯣꯖꯤꯀꯦꯜ ꯏꯐꯦꯛꯇꯁꯤꯡ ꯎꯠꯈꯤ, ꯃꯁꯤꯅꯥ ꯍꯦꯇꯦꯔꯣꯁꯥꯏꯛꯂꯤꯛ ꯁ꯭ꯠꯔꯀꯆꯔ ꯑꯁꯤꯅꯥ ꯑꯦꯟꯇꯤꯕꯦꯛꯇꯦꯔꯤꯑꯦꯜ ꯏꯐꯦꯛꯇꯁꯤꯡꯗꯥ ꯃꯔꯨꯑꯣꯏꯕꯥ ꯊꯧꯗꯥꯡ ꯂꯧꯔꯤ ꯍꯥꯌꯕꯥ ꯇꯥꯀꯏ꯫ ꯃꯇꯧ ꯑꯁꯨꯝꯅꯥ ꯀꯝꯄꯣꯁ꯭ꯠ ꯹ꯗꯥ ꯂꯩꯕꯥ ꯄꯥꯏꯔꯤꯃꯤꯗꯤꯅꯦꯊꯤꯑꯣꯟ, ꯀꯝꯄꯥꯎꯟꯗ ꯱꯰ꯗꯥ ꯊꯥꯏꯑꯣꯄꯥꯏꯔꯥꯖꯣꯜ ꯑꯃꯁꯨꯡ ꯀꯝꯄꯥꯎꯟꯗ ꯱꯱ꯗꯥ ꯂꯩꯕꯥ ꯇꯦꯠꯔꯥꯖꯤꯟ ꯔꯤꯡꯅꯥ ꯀꯝꯄꯣꯎꯟꯗꯁꯤꯡ ꯑꯁꯤꯒꯤ ꯑꯦꯟꯇꯤꯕꯦꯛꯇꯦꯔꯤꯑꯦꯜ ꯄ꯭ꯔꯣꯄꯔꯇꯤꯁꯤꯡꯗꯥ ꯃꯇꯦꯡ ꯄꯥꯡꯈꯤ, ꯃꯁꯤꯅꯥ ꯍꯦꯇꯦꯔꯣꯁꯥꯏꯛꯂꯤꯛ ꯃꯣꯗꯤꯐꯤꯀꯦꯁꯅꯒꯤ ꯃꯔꯨꯑꯣꯏꯕꯥ ꯑꯗꯨ ꯃꯈꯥ ꯇꯥꯅꯥ ꯐꯣꯡꯗꯣꯀꯈꯤ꯫
ꯁꯤꯟꯊꯦꯁꯤꯁ ꯇꯧꯔꯕꯥ ꯀꯝꯄꯥꯎꯟꯗꯁꯤꯡꯒꯤ ꯃꯅꯨꯡꯗꯥ ꯶ ꯑꯃꯁꯨꯡ ꯱꯳ꯕꯤꯅꯥ ꯃꯈꯣꯌꯒꯤ ꯑꯐꯕꯥ ꯑꯦꯟꯇꯤꯕꯦꯛꯇꯦꯔꯤꯑꯦꯜ ꯑꯦꯛꯇꯤꯚꯤꯇꯤꯁꯤꯡꯒꯤꯗꯃꯛ ꯃꯁꯛ ꯊꯣꯀꯄꯥ ꯑꯣꯏꯈꯤ꯫ ꯀꯝꯄꯣꯁ꯭ꯠ ꯶ꯀꯤ ꯃꯤꯅꯤꯃꯝ ꯏꯅꯍꯤꯕꯤꯇꯔ ꯀꯟꯁꯦꯟꯠꯔꯦꯁꯟ (ꯑꯦꯝ.ꯑꯥꯏ.ꯁꯤ.) ꯑꯁꯤ ꯹.꯷ μg/꯱꯰꯰ μL ꯑꯣꯏꯈꯤ, ꯑꯃꯁꯨꯡ ꯃꯤꯅꯤꯃꯝ ꯕꯦꯛꯇꯦꯔꯤꯁꯤꯗꯜ ꯀꯟꯁꯦꯟꯠꯔꯦꯁꯟ (ꯑꯦꯝ.ꯕꯤ.ꯁꯤ.) ꯑꯁꯤ ꯷꯸.꯱꯲꯵ μg/꯱꯰꯰ μL ꯑꯣꯏꯈꯤ, ꯃꯁꯤꯅꯥ ꯃꯦꯊꯤꯁꯤꯂꯤꯟ-ꯔꯦꯁꯤꯁ꯭ꯇꯦꯟꯇ ꯁ꯭ꯇꯥꯐꯥꯏꯂꯣꯀꯣꯀꯁ ꯑꯣꯔꯦꯁ (ꯑꯦꯝ.ꯑꯥꯔ.ꯑꯦꯁ.ꯑꯦ.) ꯀ꯭ꯂꯤꯌꯔ ꯇꯧꯕꯒꯤ ꯑꯐꯕꯥ ꯇꯧꯕꯥ ꯉꯝꯕꯒꯤ ꯃꯑꯣꯡ ꯑꯁꯤ ꯐꯣꯡꯗꯣꯀꯈꯤ꯫ ꯃꯇꯧ ꯑꯁꯨꯝꯅꯥ ꯀꯝꯄꯣꯁ꯭ꯠ ꯱꯳ꯕꯤꯅꯥ ꯁꯦꯟꯇꯤꯃꯤꯇꯔ ꯴ꯒꯤ ꯏꯅꯍꯤꯕꯤꯁꯟ ꯖꯣꯟ ꯑꯃꯁꯨꯡ ꯑꯦꯝ.ꯑꯥꯏ.ꯁꯤ. ꯑꯃꯁꯨꯡ ꯑꯦꯝ.ꯕꯤ.ꯁꯤ.ꯒꯤ ꯚꯦꯜꯌꯨ ꯅꯦꯝꯕꯥ ꯂꯩꯈꯤ, ꯃꯁꯤꯅꯥ ꯃꯁꯤꯒꯤ ꯃꯄꯥꯉ꯭ꯒꯜ ꯀꯅꯕꯥ ꯑꯦꯟꯇꯤꯕꯦꯛꯇꯦꯔꯤꯑꯦꯜ ꯑꯦꯛꯇꯤꯚꯤꯇꯤ ꯑꯁꯤ ꯀꯅꯐꯔꯝ ꯇꯧꯈꯤ꯫ ꯃꯁꯤꯒꯤ ꯔꯤꯖꯜꯇꯁꯤꯡ ꯑꯁꯤꯅꯥ ꯀꯝꯄꯣꯅꯦꯟꯇꯁꯤꯡ ꯑꯁꯤꯒꯤ ꯕꯥꯏꯑꯣꯏꯐꯤꯁꯤꯑꯦꯟꯁꯤ ꯂꯦꯄꯊꯣꯀꯄꯗꯥ ꯑꯦꯛꯔꯤꯂꯣꯍꯥꯏꯗ꯭ꯔꯦꯖꯥꯏꯗ ꯑꯃꯁꯨꯡ ꯕꯦꯟꯖꯣꯊꯤꯌꯥꯖꯣꯜ ꯐꯉ꯭ꯀꯁ꯭ꯅꯦꯜ ꯒ꯭ꯔꯨꯄꯁꯤꯡꯒꯤ ꯃꯔꯨꯑꯣꯏꯕꯥ ꯊꯧꯗꯥꯡꯁꯤꯡ ꯑꯗꯨ ꯐꯣꯡꯗꯣꯛꯂꯤ꯫
ꯃꯁꯤꯒꯥ ꯃꯥꯟꯅꯅꯥ, ꯀꯝꯄꯥꯎꯟꯗ ꯷, ꯱꯰, ꯑꯃꯁꯨꯡ ꯱꯴ꯅꯥ ꯁꯦꯟꯇꯤꯃꯤꯇꯔ ꯳.꯶꯵ꯗꯒꯤ ꯳.꯹ ꯐꯥꯑꯣꯕꯒꯤ ꯏꯅꯍꯤꯕꯤꯁꯟ ꯖꯣꯅꯁꯤꯡꯒꯥ ꯂꯣꯌꯅꯅꯥ ꯃꯌꯥꯌ ꯑꯣꯏꯕꯥ ꯑꯦꯟꯇꯤꯕꯦꯛꯇꯦꯔꯤꯑꯦꯜ ꯑꯦꯛꯇꯤꯚꯤꯇꯤ ꯎꯠꯈꯤ꯫ ꯍꯥꯌꯔꯤꯕꯥ ꯀꯝꯄꯣꯅꯦꯟꯇꯁꯤꯡ ꯑꯁꯤꯅꯥ ꯕꯦꯛꯇꯦꯔꯤꯌꯥ ꯑꯁꯤ ꯃꯄꯨꯡ ꯐꯥꯅꯥ ꯍꯥꯠꯅꯕꯥ ꯍꯦꯟꯅꯥ ꯋꯥꯡꯕꯥ ꯀꯟꯁꯦꯟꯠꯔꯦꯁꯅꯁꯤꯡ ꯃꯊꯧ ꯇꯥꯈꯤ, ꯃꯁꯤ ꯃꯈꯣꯌꯒꯤ ꯌꯥꯝꯅꯥ ꯋꯥꯡꯕꯥ ꯑꯦꯝ.ꯑꯥꯏ.ꯁꯤ. ꯑꯃꯁꯨꯡ ꯑꯦꯝ.ꯕꯤ.ꯁꯤ. ꯍꯥꯌꯔꯤꯕꯥ ꯀꯝꯄꯣꯅꯦꯟꯇꯁꯤꯡ ꯑꯁꯤ ꯀꯝꯄꯥꯎꯟꯗ ꯶ ꯑꯃꯁꯨꯡ ꯱꯳ꯕꯤꯗꯒꯤ ꯍꯦꯟꯅꯥ ꯑꯦꯛꯇꯤꯕ ꯑꯣꯏꯔꯕꯁꯨ, ꯃꯈꯣꯌꯅꯥ ꯍꯧꯖꯤꯀꯁꯨ ꯃꯔꯨꯑꯣꯏꯕꯥ ꯑꯦꯟꯇꯤꯕꯦꯛꯇꯦꯔꯤꯑꯦꯜ ꯄꯣꯇꯦꯟꯁꯤꯑꯦꯜ ꯎꯠꯂꯤ, ꯃꯁꯤꯅꯥ ꯇꯥꯛꯂꯤ ꯃꯗꯨꯗꯤ ꯍꯦꯇꯦꯔꯣꯁꯥꯏꯛꯂꯤꯛ ꯔꯤꯡꯗꯥ ꯑꯦꯛꯔꯤꯂꯣꯅꯥꯏꯠꯔꯥꯏꯜ ꯑꯃꯁꯨꯡ ꯑꯦꯟꯊ꯭ꯔꯥꯁꯤꯟ ꯃꯣꯏꯇꯤꯁꯤꯡ ꯌꯥꯑꯣꯍꯅꯕꯅꯥ ꯃꯈꯣꯌꯒꯤ ꯑꯦꯟꯇꯤꯕꯦꯛꯇꯦꯔꯤꯑꯦꯜ ꯏꯐꯦꯛꯇꯇꯥ ꯃꯇꯦꯡ ꯄꯥꯡꯏ꯫
ꯀꯝꯄꯥꯎꯟꯗꯁꯤꯡ ꯑꯁꯤꯒꯤ ꯇꯣꯉꯥꯟ ꯇꯣꯉꯥꯅꯕꯥ ꯑꯦꯛꯁꯅꯒꯤ ꯃꯑꯣꯡꯁꯤꯡ ꯂꯩ, ꯈꯔꯅꯥ ꯕꯦꯛꯇꯦꯔꯤꯌꯥ ꯁꯤꯗꯂꯒꯤ ꯃꯒꯨꯟ ꯎꯠꯂꯤ ꯑꯃꯁꯨꯡ ꯑꯇꯣꯞꯄꯥ ꯈꯔꯅꯥ ꯕꯦꯛꯇꯦꯔꯤꯑꯣꯁ꯭ꯇꯦꯇꯤꯛ ꯏꯐꯦꯛꯇ ꯎꯠꯂꯤ꯫ ꯀꯝꯄꯣꯎꯟꯗ 7, 11, 13a, ꯑꯃꯁꯨꯡ 15 ꯑꯁꯤ ꯕꯦꯛꯇꯦꯔꯤꯌꯥ ꯁꯤꯗꯜ ꯑꯣꯏ ꯑꯃꯁꯨꯡ ꯕꯦꯛꯇꯦꯔꯤꯌꯥ ꯃꯄꯨꯡꯐꯥꯅꯥ ꯍꯥꯠꯅꯕꯥ ꯍꯦꯟꯅꯥ ꯅꯦꯝꯕꯥ ꯀꯟꯁꯦꯟꯠꯔꯦꯁꯅꯁꯤꯡ ꯃꯊꯧ ꯇꯥꯏ꯫ ꯃꯁꯤꯒꯥ ꯃꯥꯟꯅꯅꯥ, ꯀꯝꯄꯥꯎꯟꯗ ꯶, ꯱꯳ꯕꯤ, ꯑꯃꯁꯨꯡ ꯱꯴ ꯑꯁꯤ ꯕꯦꯛꯇꯦꯔꯤꯑꯣꯁ꯭ꯇꯦꯇꯤꯛ ꯑꯣꯏ ꯑꯃꯁꯨꯡ ꯍꯦꯟꯅꯥ ꯅꯦꯝꯕꯥ ꯀꯟꯁꯦꯟꯠꯔꯦꯁꯟꯗꯥ ꯕꯦꯛꯇꯦꯔꯤꯌꯥ ꯍꯦꯅꯒꯠꯂꯀꯄꯥ ꯊꯤꯡꯕꯥ ꯉꯝꯃꯤ, ꯑꯗꯨꯕꯨ ꯕꯦꯛꯇꯦꯔꯤꯌꯥ ꯃꯄꯨꯡ ꯐꯥꯅꯥ ꯍꯥꯠꯅꯕꯥ ꯍꯦꯟꯅꯥ ꯋꯥꯡꯕꯥ ꯀꯟꯁꯦꯟꯠꯔꯦꯁꯟ ꯃꯊꯧ ꯇꯥꯏ꯫
ꯑꯄꯨꯅꯕꯥ ꯑꯣꯏꯅꯥ, ꯁ꯭ꯠꯔꯀꯆꯔ-ꯑꯦꯛꯇꯤꯕꯤꯇꯤꯒꯤ ꯃꯔꯤ ꯂꯩꯅꯕꯥ ꯑꯦꯅꯥꯂꯥꯏꯁꯤꯁ ꯑꯁꯤꯅꯥ ꯃꯔꯨꯑꯣꯏꯕꯥ ꯑꯦꯟꯇꯤꯕꯦꯛꯇꯦꯔꯤꯑꯦꯜ ꯑꯦꯛꯇꯤꯚꯤꯇꯤ ꯐꯪꯅꯕꯥ ꯑꯦꯛꯔꯤꯂꯣꯅꯥꯏꯠꯔꯥꯏꯜ ꯑꯃꯁꯨꯡ ꯑꯦꯟꯊ꯭ꯔꯥꯁꯤꯟ ꯃꯣꯏꯇꯤꯁꯤꯡ ꯑꯃꯁꯨꯡ ꯍꯦꯇꯦꯔꯣꯁꯥꯏꯛꯂꯤꯛ ꯁ꯭ꯠꯔꯀꯆꯔꯁꯤꯡ ꯌꯥꯑꯣꯍꯅꯕꯒꯤ ꯃꯔꯨꯑꯣꯏꯕꯥ ꯑꯗꯨ ꯐꯣꯡꯗꯣꯛꯂꯤ꯫ ꯃꯁꯤꯒꯤ ꯔꯤꯖꯜꯇꯁꯤꯡ ꯑꯁꯤꯅꯥ ꯇꯥꯛꯂꯤ ꯃꯗꯨꯗꯤ ꯁ꯭ꯠꯔꯀꯆꯔꯦꯜ ꯀꯝꯄꯣꯅꯦꯟꯇꯁꯤꯡ ꯑꯁꯤ ꯑꯣꯞꯇꯤꯃꯥꯏꯖ ꯇꯧꯕꯥ ꯑꯃꯁꯨꯡ ꯁꯣꯂꯨꯕꯤꯂꯤꯇꯤ ꯑꯃꯁꯨꯡ ꯃꯦꯝꯕ꯭ꯔꯦꯟ ꯄꯔꯃꯤꯕꯤꯂꯤꯇꯤ ꯐꯒꯠꯍꯟꯅꯕꯥ ꯃꯈꯥ ꯇꯥꯕꯥ ꯃꯣꯗꯤꯐꯤꯀꯦꯁꯅꯁꯤꯡ ꯊꯤꯖꯤꯅꯕꯅꯥ ꯍꯦꯟꯅꯥ ꯏꯐꯦꯛꯇꯤꯕ ꯑꯣꯏꯕꯥ ꯑꯦꯟꯇꯤ-ꯑꯦꯝ.ꯑꯥꯔ.ꯑꯦꯁ.ꯑꯦ.
ꯔꯤꯑꯦꯖꯦꯟꯇ ꯑꯃꯁꯨꯡ ꯁꯣꯂꯚꯦꯟꯇꯤ ꯄꯨꯝꯅꯃꯛ ꯁ꯭ꯇꯦꯟꯗꯔꯗ ꯄ꯭ꯔꯣꯁꯤꯖꯔꯁꯤꯡ (ꯑꯦꯜ ꯒꯣꯃꯍꯧꯔꯤꯌꯥ, ꯏꯖꯤꯞꯇ) ꯁꯤꯖꯤꯟꯅꯗꯨꯅꯥ ꯁꯨꯡꯗꯣꯀꯈꯤ ꯑꯃꯁꯨꯡ ꯁꯨꯡꯗꯣꯀꯈꯤ꯫ ꯃꯦꯜꯇꯤꯡ ꯄꯣꯏꯟꯇꯁꯤꯡ ꯑꯁꯤ ꯒ꯭ꯌꯥꯂꯦꯅꯀꯦꯝꯄ ꯏꯂꯦꯛꯠꯔꯣꯅꯤꯛ ꯃꯦꯜꯇꯤꯡ ꯄꯣꯏꯟꯇ ꯑꯦꯄꯥꯔꯇꯃꯦꯟꯇ ꯑꯃꯥ ꯁꯤꯖꯤꯟꯅꯗꯨꯅꯥ ꯂꯦꯄꯈꯤ ꯑꯃꯁꯨꯡ ꯃꯁꯤ ꯀꯣꯔꯔꯦꯛꯁꯟ ꯌꯥꯑꯣꯗꯅꯥ ꯔꯤꯄꯣꯔꯠ ꯇꯧꯏ꯫ ꯏꯅꯐ꯭ꯔꯥꯔꯦꯗ (ꯑꯥꯏ.ꯑꯥꯔ.) ꯁ꯭ꯄꯦꯛꯠꯔꯥ (ꯁꯦ.ꯃꯤ.−꯱) ꯑꯁꯤ ꯊꯥꯔꯃꯣ ꯏꯂꯦꯛꯠꯔꯣꯟ ꯅꯤꯀꯣꯂꯦꯠ ꯑꯥꯏ.ꯑꯦꯁ.꯱꯰ ꯑꯦꯐ.ꯇꯤ.ꯑꯥꯏ.ꯑꯥꯔ.
1H NMR ꯁ꯭ꯄꯦꯛꯠꯔꯥ ꯑꯁꯤ GEMINI NMR ꯁ꯭ꯄꯦꯛꯠꯔꯣꯃꯤꯇꯔ (GEMINI Manufacturing & Engineering, Anaheim, CA, USA) ꯑꯃꯁꯨꯡ BRUKER 300 MHz NMR ꯁ꯭ꯄꯦꯛꯠꯔꯣꯃꯤꯇꯔ (BRUKER Manufacturing & Engineering, Inc.) ꯁꯤꯖꯤꯟꯅꯗꯨꯅꯥ 300 MHzꯗꯥ ꯐꯪꯈꯤ꯫ ꯇꯦꯠꯔꯥꯃꯤꯊꯥꯏꯂꯁꯤꯂꯦꯟ (ꯇꯤ.ꯑꯦꯝ.ꯑꯦꯁ.) ꯑꯁꯤ ꯗꯤꯎꯇꯦꯔꯦꯇꯦꯗ ꯗꯥꯏꯃꯦꯊꯥꯏꯜ ꯁꯂꯐꯣꯛꯁꯥꯏꯗ (ꯗꯤ.ꯑꯦꯝ.ꯑꯦꯁ.ꯑꯣ.-ꯗꯤ.꯲)ꯒꯥ ꯂꯣꯌꯅꯅꯥ ꯏꯟꯇꯔꯅꯦꯜ ꯁ꯭ꯇꯦꯟꯗꯔꯗ ꯑꯃꯥ ꯑꯣꯏꯅꯥ ꯁꯤꯖꯤꯟꯅꯈꯤ꯫ ꯑꯦꯟ.ꯑꯦꯝ.ꯑꯥꯔ.ꯒꯤ ꯆꯥꯡꯌꯦꯡꯁꯤꯡ ꯑꯁꯤ ꯏꯖꯤꯞꯇꯀꯤ ꯒꯤꯖꯥꯒꯤ ꯀꯥꯏꯔꯣ ꯌꯨꯅꯤꯚꯔꯁꯤꯇꯤꯒꯤ ꯐꯦꯀꯜꯇꯤ ꯑꯣꯐ ꯁꯥꯏꯟꯁꯇꯥ ꯄꯥꯡꯊꯣꯀꯈꯤ꯫ ꯏꯂꯤꯃꯦꯟꯇꯔꯤ ꯑꯦꯅꯥꯂꯥꯏꯁꯤꯁ (ꯁꯤ.ꯑꯩꯆ.ꯑꯦꯟ.) ꯑꯁꯤ ꯄꯥꯔꯀꯤꯟ-ꯑꯦꯂꯃꯥꯔ ꯲꯴꯰꯰ ꯏꯂꯤꯃꯦꯟꯇꯔꯤ ꯑꯦꯅꯥꯂꯥꯏꯖꯥꯔ ꯁꯤꯖꯤꯟꯅꯗꯨꯅꯥ ꯄꯥꯡꯊꯣꯀꯈꯤ ꯑꯃꯁꯨꯡ ꯐꯪꯈꯤꯕꯥ ꯔꯤꯖꯜꯇꯁꯤꯡ ꯑꯁꯤ ꯂꯦꯄꯊꯣꯛꯂꯕꯥ ꯚꯦꯜꯌꯨꯁꯤꯡꯒꯥ ꯑꯐꯕꯥ ꯃꯑꯣꯡꯗꯥ ꯆꯨꯁꯤꯟꯅꯩ꯫
ꯑꯦꯁꯤꯗ 3 (5 mmol) ꯑꯃꯁꯨꯡ ꯊꯥꯏꯑꯣꯅꯥꯏꯜ ꯀ꯭ꯂꯣꯔꯥꯏꯗ (5 ml)ꯒꯤ ꯃꯤꯛꯁꯆꯔ ꯑꯃꯥ ꯏꯁꯤꯡꯒꯤ ꯏꯆꯦꯜ ꯑꯃꯗꯥ 65 °Cꯗꯥ ꯄꯨꯡ 4 h ꯊꯃꯖꯤꯅꯈꯤ꯫ ꯑꯍꯦꯅꯕꯥ ꯊꯥꯏꯑꯣꯅꯥꯏꯜ ꯀ꯭ꯂꯣꯔꯥꯏꯗ ꯑꯁꯤ ꯍꯟꯊꯕꯥ ꯄ꯭ꯔꯦꯁꯔꯗꯥ ꯗꯤꯁ꯭ꯠꯔꯤꯕ꯭ꯌꯨꯁꯟ ꯇꯧꯗꯨꯅꯥ ꯂꯧꯊꯣꯀꯈꯤ꯫ ꯃꯁꯤꯗꯒꯤ ꯂꯥꯀꯄꯥ ꯂꯥꯂꯍꯧꯒꯤ ꯁꯣꯂꯤꯗ ꯑꯗꯨ ꯈꯣꯃꯖꯤꯟꯗꯨꯅꯥ ꯃꯈꯥ ꯇꯥꯅꯥ ꯁꯨꯡꯗꯣꯛꯇꯨꯅꯥ ꯁꯤꯖꯤꯟꯅꯈꯤ꯫ ꯃꯦꯜꯇꯤꯡ ꯄꯣꯏꯟꯇ: ꯲꯰꯰-꯲꯰꯲ °C, ꯄꯣꯠꯊꯣꯛ: ꯸꯸.꯵%꯫ ꯑꯥꯏ.ꯑꯥꯔ.(ꯀꯦ.ꯕꯤ.ꯑꯥꯔ., ν, ꯁꯦ.ꯃꯤ.−꯱): ꯲꯲꯲꯴ (ꯁꯤ≡ꯑꯦꯟ), ꯱꯷꯳꯷ (ꯁꯤ=ꯑꯣ)꯫ 1H-NMR (400 MHz, DMSO-d6) δ (ppm): 9.26 (s, 1H, CH=), 7.27-8.57 (m, 9H, ꯍꯦꯇꯦꯔꯣꯑꯦꯔꯣꯃꯦꯇꯥꯏꯖꯦꯁꯟ)꯫ ꯱꯳ꯁꯤ ꯑꯦꯟ.ꯑꯦꯝ.ꯑꯥꯔ.(꯷꯵ ꯑꯦꯝ.ꯑꯩꯆ.ꯖꯤ., ꯗꯤ.ꯑꯦꯝ.ꯑꯦꯁ.ꯑꯣ.-ꯗꯤ.꯶) δ (ꯄꯤ.ꯄꯤ.ꯑꯦꯝ.): ꯱꯱꯵.꯱꯱ (ꯁꯤ.≡ꯑꯦꯟ), ꯱꯲꯴.꯸꯲–꯱꯳꯰.꯵꯳ (ꯁꯤ.ꯑꯩꯆ.ꯑꯦꯟꯊ꯭ꯔꯥꯁꯤꯟ), ꯱꯵꯵.꯳꯴, ꯱꯱꯴.꯹꯳ (ꯁꯤ.ꯑꯩꯆ.=ꯁꯤ–ꯁꯤ=ꯑꯣ), ꯱꯶꯲.꯲꯲ (ꯁꯤ=ꯑꯣ); ꯑꯩꯆ.ꯑꯥꯔ.ꯑꯦꯝ.ꯑꯦꯁ.(ꯏ.ꯑꯦꯁ.ꯑꯥꯏ.) ꯑꯦꯝ/ꯖꯦꯗ [ꯑꯦꯝ + ꯑꯩꯆ]+: ꯲꯹꯱.꯷꯳꯱꯱꯱꯫ ꯑꯦꯅꯥꯂꯥꯏꯇꯤꯛ ꯑꯣꯏꯕꯥ꯫ C18H10ClNO (291.73)ꯒꯤꯗꯃꯛꯇꯥ ꯂꯦꯄꯈꯤꯕꯥ: C, 74.11; ꯑꯩꯆ, ꯳.꯴꯶ ꯑꯃꯁꯨꯡ ꯑꯦꯟ. ꯑꯦꯟ, ꯴.꯸꯰ ꯑꯣꯏꯈꯤ꯫ ꯐꯪꯈꯤꯕꯥ: ꯁꯤ, ꯷꯴.꯴꯱; ꯑꯩꯆ, ꯳.꯳꯴ ꯑꯃꯁꯨꯡ ꯑꯦꯟ. ꯑꯦꯟ, ꯴.꯶꯶% ꯑꯣꯏꯈꯤ꯫
0°Cꯗꯥ, 4 (2 mmol, 0.7 g) ꯑꯁꯤ ꯑꯦꯅꯍꯥꯏꯗ꯭ꯔꯣꯁ ꯗꯥꯏꯑꯣꯛꯁꯦꯟ (20 ml)ꯗꯥ ꯌꯥꯟꯁꯤꯟꯅꯈꯤ ꯑꯃꯁꯨꯡ ꯍꯥꯏꯗ꯭ꯔꯣꯖꯦꯟ ꯍꯥꯏꯗ꯭ꯔꯦꯠ (2 mmol, 0.16 ml, 80%) ꯊꯨꯒꯥꯌꯗꯨꯅꯥ ꯄꯨꯡ 1 h ꯊꯀꯈꯤ꯫ ꯄ꯭ꯔꯦꯁꯤꯄꯤꯇꯦꯠ ꯇꯧꯔꯕꯥ ꯁꯣꯂꯤꯗ ꯑꯗꯨ ꯐꯤꯜꯇꯔ ꯇꯧꯗꯨꯅꯥ ꯈꯣꯃꯖꯤꯅꯈꯤ ꯑꯃꯁꯨꯡ ꯏꯊꯥꯅꯣꯂꯗꯒꯤ ꯔꯤꯛꯔꯤꯁ꯭ꯇꯦꯂꯥꯏꯖ ꯇꯧꯗꯨꯅꯥ ꯀꯝꯄꯣꯁ꯭ꯠ ꯶ ꯄꯤꯈꯤ꯫
ꯒ꯭ꯔꯤꯟ ꯀ꯭ꯔꯤꯁ꯭ꯇꯦꯂꯁꯤꯡ, ꯃꯦꯜꯇꯤꯡ ꯄꯣꯏꯟꯇ ꯱꯹꯰-꯱꯹꯲°C, ꯄꯣꯠꯊꯣꯛ ꯶꯹.꯳꯶%; ꯑꯥꯏ.ꯑꯥꯔ.(ꯀꯦ.ꯕꯤ.ꯑꯥꯔ.) ν=꯳꯴꯲꯴ (ꯑꯦꯟ.ꯑꯩꯆ.), ꯲꯲꯲꯸ (ꯁꯤ≡ꯑꯦꯟ), ꯱꯷꯲꯰ (ꯁꯤ=ꯑꯣ), ꯱꯶꯲꯱ (ꯁꯤ=ꯑꯦꯟ) ꯁꯦ.ꯃꯤ.−꯱. 1H-NMR (400 MHz, DMSO-d6) δ (ppm): 9.3 (br s, H, NH, ꯑꯦꯛꯁꯆꯦꯟꯖ ꯇꯧꯕꯥ ꯌꯥꯕꯥ), 7.69-8.51 (m, 18H, ꯍꯦꯇꯦꯔꯣꯑꯦꯔꯣꯃꯦꯇꯤꯛ), 9.16 (s, 1H, CH=), 8.54 (s, 1H, CH=); ꯁꯤ꯳꯳ꯑꯦꯏꯆ꯲꯱ꯑꯦꯟ꯳ꯑꯣ (꯴꯷꯵.꯵꯳)ꯒꯤ ꯑꯣꯏꯅꯥ ꯂꯦꯄꯊꯣꯀꯄꯥ ꯚꯦꯜꯌꯨ: ꯁꯤ, ꯸꯳.꯳꯵; ꯑꯩꯆ, ꯴.꯴꯵ ꯑꯃꯁꯨꯡ ꯑꯦꯟ. ꯑꯦꯟ, ꯸.꯸꯴ ꯑꯣꯏꯈꯤ꯫ ꯐꯪꯈꯤꯕꯥ: ꯁꯤ, ꯸꯴.꯰꯱; ꯑꯩꯆ, ꯴.꯳꯸ ꯑꯃꯁꯨꯡ ꯑꯦꯟ. ꯑꯦꯟ, ꯸.꯰꯵% ꯑꯣꯏꯈꯤ꯫
4 (2 mmol, 0.7 g) ꯑꯁꯤ ꯑꯦꯅꯍꯥꯏꯗ꯭ꯔꯣꯁ ꯗꯥꯏꯑꯣꯛꯁꯦꯟ ꯁꯣꯜꯌꯨꯁꯟ (ꯇ꯭ꯔꯥꯏꯏꯊꯥꯏꯂꯃꯥꯏꯅꯒꯤ ꯊꯣꯡꯅꯥꯎ ꯈꯔꯥ ꯌꯥꯎꯕꯥ) 20 mlꯗꯥ ꯌꯥꯟꯁꯤꯟꯅꯗꯨꯅꯥ, ꯐꯦꯅꯤꯂꯍꯥꯏꯗ꯭ꯔꯥꯖꯤꯟ/2-ꯑꯦꯃꯤꯅꯣꯄꯥꯏꯔꯤꯗꯤꯟ (2 mmol) ꯍꯥꯄꯆꯤꯜꯂꯨ ꯑꯃꯁꯨꯡ ꯔꯨꯝ ꯇꯦꯝꯄꯦꯔꯦꯆꯔꯗꯥ ꯃꯊꯪꯁꯤꯠꯅꯥ ꯄꯨꯡ 1 ꯑꯃꯁꯨꯡ 2 h ꯊꯃꯖꯤꯜꯂꯨ꯫ ꯔꯤꯑꯦꯛꯁꯟ ꯃꯤꯛꯁꯆꯔ ꯑꯗꯨ ꯑꯥꯏꯁ ꯅꯠꯠꯔꯒꯥ ꯏꯁꯤꯡꯗꯥ ꯊꯥꯎ ꯑꯃꯁꯨꯡ ꯃꯗꯨ ꯇꯔꯨ-ꯇꯅꯥꯅꯕꯥ ꯍꯥꯏꯗ꯭ꯔꯣꯛꯂꯣꯔꯤꯛ ꯑꯦꯁꯤꯗꯅꯥ ꯑꯦꯁꯤꯗꯤꯐꯥꯏ ꯇꯧ꯫ ꯇꯣꯈꯥꯌꯅꯥ ꯊꯃꯖꯤꯜꯂꯕꯥ ꯁꯣꯂꯤꯗ ꯑꯗꯨ ꯐꯤꯜꯇꯔ ꯇꯧ ꯑꯃꯁꯨꯡ ꯏꯊꯥꯅꯣꯂꯗꯒꯤ ꯔꯤꯛꯔꯤꯁ꯭ꯇꯦꯂꯥꯏꯖ ꯇꯧꯗꯨꯅꯥ ꯷ ꯐꯪꯒꯅꯤ ꯑꯃꯁꯨꯡ ꯕꯦꯅꯖꯤꯅꯗꯒꯤ ꯑꯃꯨꯛ ꯍꯟꯅꯥ ꯀ꯭ꯔꯤꯁ꯭ꯇꯦꯂꯥꯏꯖ ꯇꯧꯗꯨꯅꯥ ꯸ ꯐꯪꯒꯅꯤ꯫
ꯒ꯭ꯔꯤꯟ ꯀ꯭ꯔꯤꯁ꯭ꯇꯦꯂꯁꯤꯡ, ꯃꯦꯜꯇꯤꯡ ꯄꯣꯏꯟꯇ ꯱꯶꯰-꯱꯶꯲°C, ꯄꯣꯠꯊꯣꯛ ꯷꯷%; ꯑꯥꯏ.ꯑꯥꯔ.(ꯀꯦ.ꯕꯤ.ꯑꯥꯔ., ν, ꯁꯦ.ꯃꯤ.−꯱): ꯳꯲꯴꯵ (ꯑꯦꯟ.ꯑꯩꯆ.), ꯲꯲꯲꯲ (ꯁꯤ≡ꯑꯦꯟ), ꯱꯶꯹꯱ (ꯁꯤ=ꯑꯣ), ꯱꯶꯷꯱ (ꯁꯤ=ꯑꯣ) ꯁꯦ.ꯃꯤ.−꯱. 1H-NMR (400 MHz, DMSO-d6): δ (ppm): 10.88 (s, 1H, NH, ꯑꯦꯛꯁꯆꯦꯟꯖ ꯇꯧꯕꯥ ꯌꯥꯕꯥ), 9.15 (s, 1H, CH=), 8.81 (s, 1H, CH=), 6.78-8.58 (m, 23H, ꯍꯦꯇꯦꯔꯣꯑꯦꯔꯣꯃꯦꯇꯤꯛ); ꯁꯤ꯴꯲ꯑꯦꯏꯆ꯲꯶ꯑꯦꯅ꯴ꯑꯣ꯲ (꯶꯱꯸.꯶꯸)ꯒꯤ ꯑꯣꯏꯅꯥ ꯂꯦꯄꯊꯣꯀꯄꯥ ꯚꯦꯜꯌꯨ: ꯁꯤ, ꯸꯱.꯵꯴; ꯑꯩꯆ, ꯴.꯲꯴ ꯑꯃꯁꯨꯡ ꯑꯦꯟ. ꯑꯦꯟ, ꯹.꯰꯶ ꯑꯣꯏꯈꯤ꯫ ꯐꯪꯈꯤꯕꯥ: ꯁꯤ, ꯸꯱.꯹꯶; ꯑꯩꯆ, ꯳.꯹꯱ ꯑꯃꯁꯨꯡ ꯑꯦꯟ. ꯑꯦꯟ, ꯸.꯹꯱% ꯑꯣꯏꯈꯤ꯫
4 (2 mmol, 0.7 g) ꯑꯁꯤ ꯑꯦꯅꯍꯥꯏꯗ꯭ꯔꯣꯁ ꯗꯥꯏꯑꯣꯛꯁꯦꯟ ꯁꯣꯜꯌꯨꯁꯟ (ꯇ꯭ꯔꯥꯏꯏꯊꯥꯏꯂꯃꯥꯏꯅꯒꯤ ꯊꯣꯡꯅꯥꯎ ꯈꯔꯥ ꯌꯥꯎꯕꯥ) 20 mlꯗꯥ ꯌꯥꯟꯁꯤꯟꯅꯈꯤ, 2-ꯑꯦꯃꯤꯅꯣꯄꯥꯏꯔꯤꯗꯤꯟ (2 mmol, 0.25 g) ꯌꯥꯎꯍꯟꯗꯨꯅꯥ ꯑꯃꯁꯨꯡ ꯃꯤꯛꯁꯆꯔ ꯑꯗꯨ ꯔꯨꯝ ꯇꯦꯝꯄꯦꯔꯦꯆꯔꯗꯥ ꯄꯨꯡ 2 h ꯊꯃꯖꯤꯅꯈꯤ꯫ ꯔꯤꯑꯦꯛꯁꯟ ꯃꯤꯛꯁꯆꯔ ꯑꯗꯨ ꯑꯥꯏꯁ ꯋꯥꯇꯔꯗꯥ ꯊꯥꯗꯣꯀꯈꯤ ꯑꯃꯁꯨꯡ ꯗꯤꯜꯌꯨꯠ ꯍꯥꯏꯗ꯭ꯔꯣꯛꯂꯣꯔꯤꯛ ꯑꯦꯁꯤꯗꯅꯥ ꯑꯦꯁꯤꯗꯤꯐꯥꯏ ꯇꯧꯈꯤ꯫ ꯁꯦꯃꯈꯤꯕꯥ ꯄ꯭ꯔꯦꯁꯤꯄꯤꯇꯦꯠ ꯑꯗꯨ ꯐꯤꯜꯇꯔ ꯇꯧꯗꯨꯅꯥ ꯕꯦꯅꯖꯤꯅꯗꯒꯤ ꯔꯤꯛꯔꯤꯁ꯭ꯇꯦꯂꯥꯏꯖ ꯇꯧꯈꯤ, ꯃꯁꯤꯅꯥ 146-148 °Cꯒꯤ ꯃꯦꯜꯇꯤꯡ ꯄꯣꯏꯟꯇ ꯑꯃꯁꯨꯡ 82.5%ꯒꯤ ꯄꯣꯠꯊꯣꯛ ꯂꯩꯕꯥ 8ꯒꯤ ꯒ꯭ꯔꯤꯟ ꯀ꯭ꯔꯤꯁ꯭ꯇꯦꯂꯁꯤꯡ ꯄꯤꯈꯤ; ꯏꯅꯐ꯭ꯔꯥꯔꯦꯗ ꯁ꯭ꯄꯦꯛꯠꯔꯦꯝ (KBr) ν: 3148 (NH), 2222 (C≡N), 1665 (C=O) cm−1. 1H NMR (400 MHz, DMSO-d6): δ (ppm): 8.78 (s, H, NH, ꯑꯦꯛꯁꯆꯦꯟꯖ ꯇꯧꯕꯥ ꯌꯥꯕꯥ), 9.14 (s, 1H, CH=), 7.36-8.55 (m, 13H, ꯍꯦꯇꯦꯔꯣꯑꯦꯔꯣꯃꯦꯇꯥꯏꯖꯦꯁꯟ); ꯁꯤ ꯲꯳ꯑꯦꯏꯆ꯱꯵ꯑꯦꯅ꯳ꯑꯣ (꯳꯴꯸.꯳꯸)ꯒꯤꯗꯃꯛꯇꯥ ꯂꯦꯄꯈꯤꯕꯥ: ꯁꯤ, ꯷꯹.꯰꯷; ꯑꯩꯆ, ꯴.꯳꯳ ꯑꯃꯁꯨꯡ ꯑꯦꯟ. ꯑꯦꯟ, ꯱꯲.꯰꯳ ꯑꯣꯏꯈꯤ꯫ ꯐꯪꯈꯤꯕꯥ: ꯁꯤ, ꯷꯸.꯹꯳; ꯑꯩꯆ, ꯳.꯹꯷ ꯑꯃꯁꯨꯡ ꯑꯦꯟ. ꯑꯦꯟ, ꯱꯲.꯳꯶% ꯑꯣꯏꯈꯤ꯫
ꯀꯝꯄꯣꯁ꯭ꯠ 4 (2 mmol, 0.7 g) ꯑꯁꯤ ꯁꯨꯡꯕꯥ ꯗꯥꯏꯑꯣꯛꯁꯦꯟ 20 ml (ꯇ꯭ꯔꯥꯏꯏꯊꯥꯏꯂꯃꯥꯏꯅꯒꯤ ꯊꯣꯡꯅꯥꯎ ꯈꯔꯥ ꯑꯃꯁꯨꯡ ꯊꯥꯏꯑꯣꯌꯨꯔꯤꯌꯥ/ꯁꯦꯃꯤꯀꯥꯔꯕꯥꯖꯤꯗ 2 mmol ꯌꯥꯎꯕꯥ)ꯗꯥ ꯌꯥꯟꯁꯤꯟꯅꯈꯤ ꯑꯃꯁꯨꯡ ꯔꯤꯐ꯭ꯂꯛꯁ ꯃꯈꯥꯗꯥ ꯄꯨꯡ 2 h ꯊꯃꯖꯤꯅꯈꯤ꯫ ꯁꯣꯂꯚꯦꯟꯇꯤ ꯑꯗꯨ ꯚꯦꯀꯨꯏꯃꯗꯥ ꯏꯚꯥꯛꯌꯨꯑꯦꯠ ꯇꯧꯈꯤ꯫ ꯔꯦꯁꯤꯗꯦꯟꯇ ꯑꯗꯨ ꯗꯥꯏꯑꯣꯛꯁꯦꯅꯗꯒꯤ ꯔꯤꯛꯔꯤꯁ꯭ꯇꯦꯂꯥꯏꯖ ꯇꯧꯗꯨꯅꯥ ꯃꯤꯛꯁꯆꯔ ꯑꯃꯥ ꯄꯤꯈꯤ꯫